Incidence and Associated Factors of Perioperative Respiratory Adverse Events Among Pediatric Patients who Underwent Surgery Under General Anesthesia at Tikur Anbesa Specialized Hospital in Addis Ababa, Ethiopia 2024/25
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Date
2025-04-05
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Addis Ababa University
Abstract
Background: Perioperative respiratory adverse events (PRAEs) are the most frequent complications in pediatrics which frequently result in morbidity and mortality. They are accountable for 75% of perioperative critical incidents and 33% of cardiac arrests.
Objective: To assess the incidence and associated factors of perioperative respiratory adverse events who underwent surgery under general anesthesia among pediatric patients at Tikur anbesa specialized hospital, Adiss Ababa, Ethiopia.
Methods: An institution based cross sectional study was conducted among 176 pediatric patients aged 0 to 12 years who underwent elective and emergency surgery over three month period. Systemic random sampling was used to select patients. Data was collected through structured questionnaires and medical record reviews. Analysis was done by using SPSS 25. Logistic regression was used to identify associated factors and a p-value < 0.05 at 95%
confidence intervals was considered as statistical significance.
Result: The overall incidence of perioperative respiratory adverse events was 20% (n=36). ASA class 2 and 3 (AOR=8.7, 95%CI=2.74, 27.84) and (AOR=4.9, 95%CI=1.23, 19.77) respectively, upper respiratory tract infection (AOR=7.6, 95%CI=2.14, 27.16). and duration of surgery more than 1 hr (AOR=4.4, 95%CI=1.45, 13.28). were independent predictors for perioperative respiratory adverse events.
Conclusion: A significant level 20% of the study participants had preoperative respiratory adverse event. Factors that were associated with were history of Upper respiratory tract infection, increasing American society of anesthesiologist physical status and long duration of surgical procedure.
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Perioperative respiratory adverse event, pediatric anesthesia, perioperative period, adverse event, risk factors