Assessment of Biosafety Practice and Associated Factors in Clinical Laboratory Workers Among Government Hospitals in Addis Ababa, Ethiopia

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Addis Ababa University


Background: Biosafety is an important practice in all laboratory settings especially in developing countries where standard operating procedures are lacking. There is only limited information about biosafety practices in government hospital laboratories in Addis Ababa. Objective: To assess the situation of biosafety practice and associated factors in clinical laboratory workers among government Hospitals in Addis Ababa, Ethiopia Method: Cross-sectional study design was conducted from March to May 2014; in all government Hospitals of Addis Ababa. A total of 290 laboratory professionals were participated about their biosafety practice and its associated factors using structured questionnaire to assess the structural and functional aspects of Biosafety Practice of laboratories. Data were coded and entered by Epi Info and Exported to SPSS V.20 for analysis. Bivariate and multivariate analysis were also used to identify factors that affect the outcome variable and to examine the effect of selected variables on laboratory personnel practice toward biosafety practice by using Odds Ratio (OR) with a 95% Confidence Interval. P- Value less than 0.05 were taken as statistically significant. Variables that were found with a statistically significant association (p<0.05) at bivariate logistic analysis were entered and analyzed by multiple logistic regression analysis. Results: - In this study a total of 290 laboratory professionals were involved. Out of those subjects the biosafety practice rates of protective barrier were 76.2%. The major factor for biosafety practice were practice of performing a written procedure for the clean-up of spills (AOR=2.31; CI 1.21-4.42), those who were practice of decontamination and wastes before disposal (AOR=2.69; CI 1.49-4.86) and those who got information in Participating a biosafety practice (AOR=5.07; CI 1.66-15.52) Conclusion: - This study revealed that there is an achievement of a minimum requirement of biosafety practice among studied laboratory personnel. Practice of performing clean-up of spills, practice of decontamination and wastes before disposal and information in participating a biosafety practice are a significant association with biosafety practice.



Clinical Laboratory