Prevalence of Mdr-Tb and Treatment Outcome Among Tuberculosis Patients Attending At St. Peter Tb Specialized Hospital Addis Ababa, Ethiopia
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Date
2014-06
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Addis Ababa University
Abstract
Background-The emergence of drug resistance tuberculosis, particularly MDR-TB has become a
major public health problem in a number of countries and an obstacle to the global TB control
efforts. Information on treatment outcomes among hospital patients with multi drug resistant
tuberculosis (MDR-TB) and tuberculosis were scare in Ethiopia.
Objective:- The study was carried out the prevalence of MDR-TB an Treatment outcome
among tuberculosis patients attending at St. Peter TB specialized Referral Hospital from January
1, 2011to end of December 2013.
Method:- The study design was descriptive retrospective cross-sectional study using data collected
from medical records, radiological reports, bacteriological reports and consultant reports of MDR TB on
680MDR tuberculosis patients. Data has taken from January 2011 to end of December 2013 .Frequency,
median and range were computed for descriptive analysis. Binary and multiple variety analysis were
computed for inferential analyze. The ethical approval was obtained from AAU Institutional Review
Board (IRB).Patient care records were kept confidential.
Result: The median age was 29 years (inter-quartile range 24– 37), with similar sex proportions
(53.5% female).The number of MDR TB patient vary with their residence .Most of the patients
were from Addis Ababa, the capital city of Ethiopia 385 (56;4%) followed by Oromo region
144(21%).. MDR TB prevalence increase from time to time as the study showed that 22.9% in
2011 to 48$ in 1013, There were strong association between the contracting co infection and
MDRTB unsuccessful outcome.
Conclusion and recommendation: MDR TB prevalence increase from time to time. There were
strong association between the contracting co infection and MDRTB unsuccessful treatment
outcome. Therefore; use of rapid, sensitive and specific methods for detecting MDR-TB must be
recommended to combat the problem of MDR-TB.
Keyword- MDR-TB, Resistance TB, Anti- TB Regimen
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Keywords
MDR-TB, Resistance TB, Anti- TB Regimen