Outcome of Bubble CPAP for the Management of Preterm Neonates with RDS and Associated Factors at NICU, TASH, Addis Ababa; Hospital Based Cross-Sectional Study
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Date
2025-04-13
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Addis Ababa University
Abstract
Background: Respiratory distress syndrome is among the major complications of preterm birth. In developed countries the infant mortality rate from RDS has significantly reduced. But in resource restricted setting RDS is still among the commonest cause of mortality among preterm neonates(1) Continuous positive airway pressure ( CPAP ) has become a useful modality in management of respiratory distress in preterm babies. It is found to be safe and effective means of treating mild and moderate RDS and apneas of prematurity(2). CPAP started at birth is as effective as prophylactic or early surfactant and is associated with a reduction in BPD(3). Bubble CPAP , when used appropriately , is more cost effective , less intensive , requires less training and has lower risk of complications(4)
Method: A hospital based cross- sectional study was conducted on preterm neonates with RDS on bubble CPAP admitted at TASH ,NICU . Participants were selected using a simple random sampling technique. Data was collected through chart review . Data was entered into the statistical package for social sciences version 25 ( SPSS ) for subsequent descriptive and analytical statistics where applicable . Statistically significant association was taken for p value of < 0.05.
Result: Among the 186 neonates included in the study, the occurrence of death as an outcome of bubble CPAP was 33 (17.7 %) . And being very preterm (28-31+6 weeks ) and having sepsis as a concomitant illness were identified as a statistically significant association with having death as an outcome of bubble CPAP. Conclusion: This study revealed a relatively higher level of death as an outcome of bubble CPAP and the factors associated were being very preterm ( 28 - 31 +6 weeks ) and having sepsis as a concomitant illness.
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CPAP for the management of preterm neonates