Major Causes and Factors associated the outcome of patients with Upper GI bleeding in Tikur Anbessa specialized hospital, Addis Ababa, Ethiopia: Institution Based Prospective cohort study

dc.contributor.advisorMerdassa,Guda(Ass.Prof.)
dc.contributor.advisorBerhe,Rezene(Ass.Prof.)
dc.contributor.authorW/Giorgis,Blen
dc.date.accessioned2025-08-13T07:53:14Z
dc.date.available2025-08-13T07:53:14Z
dc.date.issued2023-10
dc.description.abstractBackground: Upper gastrointestinal bleeding refers to blood loss within the intraluminal gastrointestinal tract from any location between the upper esophagus to the duodenum at the level of the ligament of Treitz. Bleeding from the upper gastrointestinal tract is approximately five times more common than from the lower gastrointestinal tract. The incidence of upper GI bleeding ranges from 50 to 150/100,000 population annually, and as many as 70% of acute upper GI bleeding episodes occur in patients older than 60 years. This study aimed to assess the Rebleeding and Death at 30 days of the patient’s outcome with those upper GI bleeding in TASH, Addis Ababa, Ethiopia. Method: The study was an institution-based prospective cohort study. A total of 123 patients who had upper GI bleeding were enrolled in this study, and associated factors studied. Data samples were collected from the study participants, together with associated sociodemographic, endoscopic findings, lab profiles, potential risk factors, and other important questionnaires, at the TASH GI Clinic endoscopy unit from January 2023 to September 2023. Result: The mean age of participants with GIB was 41.28 ± 16.352 (range 13–84 years). About 67 (54.5%) of patients were under 40 years of age. Out of 123 patients admitted with upper GI bleeding, 73 (58.5%) of them stayed in hospital for less than 3 days, rebleeding at 30 days occurred in 21 (17.1%) of patients, and death at 30 days occurred in 17 (13.8%). Conclusion: In this study, the mortality rate at 30 days was high about 13.8% and in 17.1% of patients, rebleeding occurred within 30 days. Variceal bleeding was found the most common cause of upper gastrointestinal bleeding accounting for 53.7% of patients.
dc.identifier.urihttps://etd.aau.edu.et/handle/123456789/6679
dc.language.isoen_US
dc.publisherAddis Ababa University
dc.subjectDeath at 30 days
dc.subjectUpper GI bleeding
dc.subjectEndoscopy
dc.subjectRebleeding at 30 days.
dc.titleMajor Causes and Factors associated the outcome of patients with Upper GI bleeding in Tikur Anbessa specialized hospital, Addis Ababa, Ethiopia: Institution Based Prospective cohort study
dc.typeThesis

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