Characteristic and Outcomes of Mechanically Ventilated Patients at Adult ICU of Selected Public Hospitals in Addis Ababa, Ethiopia, 2021.

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Addis Abeba University


Abstract Introduction: Mechanical ventilation is the primary method of supporting organ function in patients treated in intensive care units. The information on the characteristics and outcomes of patients requiring mechanical ventilation is critical for the understanding of reasons for mortality. However, there is a scarce of literature in developing countries, including Ethiopia. Objective: The objective of this study is to assess the characteristics and outcomes of mechanically ventilated adult ICU patients in selected public hospitals, Addis Ababa, Ethiopia, from 2019 to 2020. Method: An institutional-based quantitative cross-sectional study design was employed. All Adult patients who were mechanically ventilated in adult ICU for at least 24 hours were included and the collected data was evaluated with Statistical Package for the Social Sciences version 25 software. Result: Of 181 mechanically ventilated patients, 98(54.4%) were male. The main reason for ventilation was respiratory failure. Volume-controlled ventilation was the preferred initial ventilation mode followed by pressure-controlled ventilation. The main weaning technique employed for the survived patients was CPAP followed by a T-tube trial. The mean duration of stay in the ventilator was 7.09± 6.06, and the length of stay in ICU was 10.04 ± 10.242 days. The mortality rate in mechanically ventilated patients was 41.7%. The mortality rate was higher in patients with cardiac diseases. Inotropic use, sedation use, and length of stay on mechanical ventilator independently associated with mortality. Conclusion and recommendation: The mortality rate of mechanically ventilated patients in the selected public hospitals was high. It is better to use a Customized severity score while admitting patients to ICU and implement different quality improvement projects.



Mechanical Ventilation, Characteristics, Outcome