Emergency Admission Among Cardiovascular Disease Patients; Outcome,Risk Factors and Drug-Related Admission, at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia: a Prospective Observational Study.

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Date

2024-02

Authors

Husein,Hikma

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Publisher

Addis Ababa University

Abstract

Background: In Ethiopia, the prevalence of cardiovascular diseases is rising, with varying prevalence from 1 to 20 percent across the nation. Moreover, drug-related hospital admissions are a common issue among these patients because of the greater number of medications required, the multiple issues caused by cardiovascular illnesses, and the usage of pharmaceuticals with a limited therapeutic index. Objective: This study aims to evaluate the results of cardiovascular patients treated in the emergency room of Tikur Anbessa Specialized Hospital, as well as the frequency of drug-related emergency admissions and the factors linked to both the drug-related admissions and the patient's outcome. Methodology: A prospective observational study was conducted from September to December 2022 on patients with cardiovascular illness who came to Tikur Anbessa Specialized Hospital's adult emergency department. All patients who visited ED during this time and met the requirements for inclusion was counted in the study. A questionnaire was used to gather data, and SPSS version 25 was used for analysis. While factors associated with drug-related emergency admission were identified by logistic regression analysis, cox regression analysis was used to estimate factors associated with emergency department survival. Result: In total, 401 patients made up the study; 51.1% of the patients were male and the median age was 50. Of the patients admitted to the emergency room, 9.5% passed away during the study period. Poly-pharmacy, diagnosis with dilated cardiomyopathy and atrial fibrillation, and history of smoking are associated with a higher mortality rate in these patients. 23% of all admission was due to drug related problems, with non-adherence being the most common cause. Conclusion: A mortality rate of 9.5% was found in cardiovascular disease patients, and the prevalence of drug related emergency admission among cardiovascular disease patients was 23% in this study.

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Keywords

Cardiovascular Disease, Survival, Drug-Related Emergency Admission, Ethiopia

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