Browsing by Author "Tsegaye Wedajo"

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    Incidence and Associated Factors for Post Propofol Induction Hypotension During Elective General Surgery at Adama Hospital Medical College,Oromia ,Ethiopia,2020:a Cross-Sectional Study.
    (Addis Abeba University, 2020-11) Tsegaye Wedajo; Girma Betelihem; Fentie Fisseha
    Background: Induction agents are drugs that, when given IV in an appropriate dose, cause a rapid loss of consciousness. Propofol is a common anesthetic agent for the induction of general anesthesia. During anesthesia, maintenance of adequate tissue perfusion is mandatory. However, rapid infusion of propofol often causes hypotension. Objectives: To determine the incidence and associated factors for hypotension after propofol induction in patients undergoing general surgery from January to May 30, 2020 at Adama Hospital Medical College. Method: Institutional based cross sectional study was conducted on 286 on patients undergoing general surgery from January, to May, 30, 2020 at Adama Hospital Medical College, Oromia, Ethiopia using structured questionnaire. Systematic random sampling technique was used to select the sample. Both binary and multiple variabe logistic regression analysis were done for associated factors. Level of statistical significance was declared at p-value less than 0.05. Results: The incidence of hypotension among clients undergoing general surgery after propofol induction was 60.4%. Age >=60year AOR=3.01; 95%CI: (1.41- 6.41), baseline MAP 60100mm Hg AOR=3.78; 95%CI: (1.91-7.47), dose of propofol AOR= 2.40; 95%CI: (1.26-4.55), dose of pethidine AOR=2.00; 95%CI: (1.09-3.69) were identified as associated factors of hypotension among clients undergone general surgery after propofol induction. Conclusion: Hypotension after propofol induction was a common problem in patients undergoing general surgery. Age, baseline MAP, dose of propofol and pethidine are the clinical factors associated with post-propofol induction hypotension. The use of these factors to estimate risk of this hypotension might allow the avoidance and early treatments of hypotension during general surgery.