Browsing by Author "Seid,Awol"

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    Determinants of early and late onset preeclampsia among women delivered at Ghandi memorial hospital,2023: a case control study
    (Addis Ababa University, 2023-06) Seid,Awol; Hussien,Heyria(Msc)
    Background: preeclampsia is pregnancy induced hypertensive disorder characterized by elevated blood pressure and proteinuria. It can be classified into early onset preeclampsia (EOPE) and late onset preeclampsia (LOPE) based on gestational age. LOPE shares ∼80 to 95%of all preeclampsia cases worldwide and its incidence were 0.3 and 2.7%, EOPE, LOPE respectively. Objective: The primary purpose of this study was to identify determinants of early and late onset preeclampsia among women delivered at Ghandi memorial hospital from January,2021-2022. Method: Hospital based unmatched case control study was conducted on 174 cases and 348 controls among women delivered at Ghadi memorial hospital from March 20, 2023 to April 20,2023. Women with confirmed preeclampsia and atypical preeclampsia were considered as cases and normotensive women will be considered as controls. Data was collected by using kobo collect application and exported into SPSS version 26 for analysis. Logistic regression was done. Finally, a p-value of less than 0.05 was declared as significant. Result: Hypertension history in her family and history of high blood pressure in the previous pregnancy were significantly associated with early onset preeclampsia with (AOR=6.8, CI=1.64- 28.6) and (AOR=9.8, CI=1.69-56.8) respectively. Advanced maternal age when first time pregnancy, history of UTI during pregnancy, history of contraceptive use, and lack of ANC visits with respective (AOR=14.55, CI=1.28-165), (AOR=8.36, CI=2.05-34.11), (AOR=4.34, CI=1.31- 14.41) and (AOR=3.29, CI=1.47-7.35) respectively. Conclusion: Generally, family history of hypertension, history of gestational hypertension and ANC visit were associated with increased risk of both early and late onset preeclampsia in this study. Nevertheless, history of UTI during pregnancy, advanced maternal age at first time pregnancy, lack of ANC visit and history of contraceptive use were found to be the risk factor for late onset preeclampsia. It is better to recruit specialty trained professionals and work together with primary health facilities to create a conducive environment so that patients with preeclampsia and other associated illnesses can be treated, educated and can have regular follow up.