Browsing by Author "Negussie Taffa"

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    Malaria in Pregnancy in Three Woredas of East Shoa.
    (Addis Abeba Universty, 1994-05) Negussie Taffa; Ahmed Ali
    A cross-sectional, community based study of malaria was conducted from September-December 1993 , in an un stable malaria endemic area in Eastern Shoa , Ethiopia, to determine the prevalence and document the clinical features and treatment responses in pregnant and non pregnant women. A total of 1,767 women were studied. Ninety (11.3%) pregnant and 63{6.6%) non pregnant women were found to have malaria parasitemia (P=O.OOl). The rate in primigravidae was higher than in multi gravidae, 212(12.24%) and 31 4{11 .4%) respectively, though the difference was not statistically significant. Over all Plasmodial prevalence showed 49.7% Plasmodium v i vax and 50.3% Plasmodium falciparum. Mean gestational age o f the pregnant women was 21.09± 10.2 weeks with Peak malaria parasitemia around mid pregnancy. Majority of cases were symptomatic during diagnosis and symptoms were not different between pregnant and non pregnant. Conjunctival pallor was more documented in pregnant than in non pregnant (OR = 3.04, 95% CI.1.47,6 . 33). Mean haematocritin the pregnant was 30.3± 4.6% and 33.4± 6.8% in the non pregnant (P= 0.000 1) . Primigravidae showed lower haematocrit values a nd higher mean parasite counts when compared to multigravidae (P =0.03 and 0.06 respectively). Mean asexual malaria parasite count was 6, 561± 5,259/micro litter of blood and 4,598± 4,275/micro litter of blood in pregnant and non pregnant respectively (P= 0.01). Clinical responses in both groups were not significantly different. Findings are discussed and recommendations made regarding future studies.