Browsing by Author "Messele Tamerat"

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    Seroprevalence and Risk Factors of HBV, HIV and Syphilis Infections among Pregnant Women Attending at Gandhi Memorial Hospital, Addis Ababa, Ethiopia.
    (Addis Abeba University, 2021-09) Messele Tamerat; Desta Kassu ; Getachew Ashebir
    Background: HIV, viral hepatitis, and Syphilis infection among pregnant women have a seriousoutcome on maternal and newborn baby in worldwide. Sexually transmitted infections causeconsiderable morbidity worldwide, especially among women. and as hidden epidemics oftremendous health and economic consequence in the world. Objective: to determine Seroprevalence & risk factors of HIV, HBV, and Syphilis Infectionamong pregnant women attending Gandhi Memorial Hospital, Addis Ababa Ethiopia from March to June, 30 2021. Methods: Hospital-based cross-sectional study was conducted among 384 pregnant women fromMarch to June,, 2021. A structured questionnaire was used to collect socio-demographic characteristics and predictors of HIV, hepatitis B, and Syphilis infections through face-to-faceinterviews. A venous blood sample of 5mL was collected from study participants, and thenSeparate serum was screened for anti-HIV, HBsAg, and Trepollema pallidum antibodies usingrapid test kits and further Verified by Wanti enzyme-linked immunosorbent assay. The data wereentered using Epi Info version 7.2.4 and exported to SPSS version 25, and Logistic regressionanalysis was used to identify predictors of HIV1/2, hepatitis B, Syphilis infections. A p-valueless than 0.05 was considered statistically significant. Results: The overall seroprevalence of HIV1/2, Hepatitis B, and Syphilis infections were(3.9%), (3.4%) and (2.3%), respectively. In multivariate analysis, The prevalence of HIV wassignificantly higher in More than one Sex Partners [AOR 3 95%CI (1.4 - 6.1)], [p=<0.002], and The risk for HBV infection more than one Sexual partner [4.3 95%CI (1.17- 8.3],[p=0.003]. Therisk for syphilis occurrence was significantly higher among the history of More than one SexPartners [AOR 3 95%CI (1.2 - 5.2)], [p=<0.001]. HIV co-infection was present in 23.1% and44.4% of hepatitis B virus and Treponema pallidum positive pregnant women respectively. Conclusion: Overall, prevalence of syphilis and HIV were relatively higher with a youngwomen andin womenliving in Addis Ababa, HBV infection was higher only in Non educatedwomen, More than one Sex partner is a Major predictor of STI infections. Therefore;Equalattention is Needed to HBV and syphilis infection like HIV to control further transmission andthe associated morbidity and mortality .