Browsing by Author "Mequanint, Gashaw"

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    Prevalence of Mdr-Tb and Treatment Outcome Among Tuberculosis Patients Attending At St. Peter Tb Specialized Hospital Addis Ababa, Ethiopia
    (Addis Ababa University, 2014-06) Mequanint, Gashaw; Mengistu, Zuriyash (PhD)
    Background-The emergence of drug resistance tuberculosis, particularly MDR-TB has become a major public health problem in a number of countries and an obstacle to the global TB control efforts. Information on treatment outcomes among hospital patients with multi drug resistant tuberculosis (MDR-TB) and tuberculosis were scare in Ethiopia. Objective:- The study was carried out the prevalence of MDR-TB an Treatment outcome among tuberculosis patients attending at St. Peter TB specialized Referral Hospital from January 1, 2011to end of December 2013. Method:- The study design was descriptive retrospective cross-sectional study using data collected from medical records, radiological reports, bacteriological reports and consultant reports of MDR TB on 680MDR tuberculosis patients. Data has taken from January 2011 to end of December 2013 .Frequency, median and range were computed for descriptive analysis. Binary and multiple variety analysis were computed for inferential analyze. The ethical approval was obtained from AAU Institutional Review Board (IRB).Patient care records were kept confidential. Result: The median age was 29 years (inter-quartile range 24– 37), with similar sex proportions (53.5% female).The number of MDR TB patient vary with their residence .Most of the patients were from Addis Ababa, the capital city of Ethiopia 385 (56;4%) followed by Oromo region 144(21%).. MDR TB prevalence increase from time to time as the study showed that 22.9% in 2011 to 48$ in 1013, There were strong association between the contracting co infection and MDRTB unsuccessful outcome. Conclusion and recommendation: MDR TB prevalence increase from time to time. There were strong association between the contracting co infection and MDRTB unsuccessful treatment outcome. Therefore; use of rapid, sensitive and specific methods for detecting MDR-TB must be recommended to combat the problem of MDR-TB. Keyword- MDR-TB, Resistance TB, Anti- TB Regimen