Browsing by Author "Lijaemiro, Hana(MSc)"

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    Prevalence of Thrombocytopenia and its Associated Factors among Neonates Admitted to Neonatal Intensive Care Unit at Public Hospitals of Addis Ababa in 2020/21G.c.
    (Addis Abeba University, 2021-05) Wodaje, Markos; Tadele, Niguse(MSc,AssistantProfessor); Lijaemiro, Hana(MSc)
    Background Thrombocytopenia is one of the most frequent hematologic disorders encountered in the sick neonate. This is evidenced by a fairly high prevalence among neonates admitted to the neonatal intensive care unit 22%-35%, especially in very-low-birth-weight and preterm neonates its prevalence is up to 70%-80%. In Africa, the prevalence of neonatal thrombocytopenia in Nigeria is 53%, 12.4% in Tunisia, and 16.2% in Libya. However, in Ethiopia, no study assessed both its prevalence and associated factors. This study assessed the prevalence of thrombocytopenia and its associated factors among neonates admitted to neonatal intensive care unit at public hospitals in Addis Ababa in 2020/21. Methodology: Institution based cross sectional study was conducted at NICU of selected Addis Ababa public hospitals from February 15 th to March 15 th , 2021. Single population proportion formula is used to determine sample size. The final sample size is 423. Data collected by using pretested, data extraction checklist for chart review by data collector. The collected data entered using Epi data and exported to SPSS version 25 for analysis. Variables that have P-value <0.05 in bivarite entered in to multivariable logistic regression model to control for confounder. Statistical significance declared at p-value <0.05. Results: The prevalence of neonatal thrombocytopenia in the study area is 66%.In this study variables such as eclampsia(AOR=4.8, 95%CI: 1.66-13.94), Prolonged rupture of membrane(AOR=0.26, 95%CI:0.101-0.669), Intra uterine growth retardation(AOR=0.26, 95%CI: 0.1-0.68), neonatal sepsis (AOR=11.98, 95%CI: 4.023-35.7), Perinatal asphyxia(AOR=6.68, 95%CI: 1.616-27.6), Necrotizing enterocolitis (AOR=14.6, 95%CI: 2.84-75.61) and prolonged nothing per oath(AOR=0.243,95%CI: 0.084-0.705) were factors associated with neonatal thrombocytopenia. Conclusion and recommendation: Prevalence of neonatal thrombocytopenia in Addis Ababa public hospitals neonatal intensive care unit is high. Therefore, identifying factors associated with it used as an input in reducing the problem.