Browsing by Author "Kefyalew, Endashaw"

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    Clinical characteristics and Endoscopic outcomes of patients who underwent UGIE for an indication of dyspepsia at Tikur Anbesa Hospital Gastroenterology referral clinic from December 1, 2015- December 30 2019.
    (Addis Abeba University, 2020-12) Kefyalew, Endashaw; Dr. Sultan, Amir(MD, internist, Consultant Gastroenterologist)
    Background: Dyspepsia is a frequent syndrome in our country, where there is limited endoscopy service and high prevalence of Helicobacter pylori (H. pylori) infection with some having an organic cause while others have functional dyspepsia. Endoscopy is the most accurate method of diagnosis of most endoscopically positive conditions associated with dyspepsia, including gastric cancer, peptic ulcer disease, esophagitis and gastro- duodenitis. Helicobacter pylori infection is associated with various upper gastrointestinal pathologies. Objective: The purpose of this study is to Clinical characteristics and Endoscopic outcomes of patients who underwent UGIE for an indication of dyspepsia at Tikur Anbesa Hospital Gastroenterology referral clinic. Methods: A Hospital based- Retrospective cross-sectional study was conducted using pretested, structured questionnaires to determine clinical characteristics of patients between 17-76 years’ old who underwent endoscopic procedure at Tikur Anbesa Hospital Gastrointestinal referral clinic. The study is conducted from April 2020-september 2020 G.C. A sample of 270 patients were included in the study. Based on the structured questionnaire, presenting symptom, alarm symptom, H.pylori test result and endoscopic finding and risk factors are assessed by the investigator. Organic dyspepsia findings were analyzed with different variables to verify statistically significant associations. Result: Two hundred seventy patients were included and analyzed in the study. The mean age was 38 years and Men comprised 58.5% of the study. 37 % of the patients reported alarm symptoms. The prevalence of H. pylori infection was 37.8 %. Endoscopic finding constitutes Normal, 29%, Ulcer disease, 16% (duodenal in 13% and gastric ulcer in 3%), Gastropathy/Gastritis 33 %, 13% had GERD and esophageal erosion and gastric mass account for 2.2 %. Ulcer diseases were found to have statistically significant association with H. pylori infection OR, (0.38 95% CI, (0.143-0.552) and alarm symptom (iron deficiency anemia and persistent vomiting), p <0.05. Conclusion: The endoscopic diagnosis in our setting showed predominance of abnormal findings and of this ulcer disease is the major endoscopic outcome with strong associations with Helicobacter pylori infection and GERD diagnosis was also shown to be frequent endoscopic diagnosis among our dyspeptic patient. Whereas cancer was an uncommon finding, despite the high prevalence of H. pylori.