Browsing by Author "H/mariam,Workineh"

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    Assessment of serum lipid profiles and electrolytes among type II diabetic patients with and without hypertension attending Wolaita Sodo University comprehensive specialized Hospital, Wolaita, South Ethiopia.
    (Addis Ababa University, 2024-01) H/mariam,Workineh; Edao,Abebe(MSc, Ass. Prof.); Alem,Mekdes(MSc)
    Background: Diabetes is disease characterized by hyperglycemia with a disturbance of metabolism ofcarbohydrates, lipids and electrolytes. Coexistence of high blood pressure, dyslipidemia and electrolytes disturbance with diabetes has a risk for increased morbidity and mortality. Despite these alarming figures, data on the biochemical impact of coexisting diabetes and hypertension — specifically lipid profile and electrolyte variations — are limited in the Ethiopian population and study area. Objective: To assess and compare serum lipid profiles and electrolytes level among type II diabetic patients with and without hypertension attending wolaita sodo university comprehensive specialized hospital, wolaita, South Ethiopia, from January 2024 to March 2024. Methods: Hospital based comparative cross-sectional study was conducted on 66 hypertensive diabetic and 66 normotensive diabetic patients. Trained data collectors gathered the data using a structured questionnaire. Serum lipid profiles (HDL, LDL, TG and TC) and electrolytes (Sodium, Potassium and Chloride) were measured by Dimension EXL-200 analyzer. During analysis, Chisquare is used to compare the study groups by mean level. Binary logistic regression was used to determine associated factors with lipid profiles and electrolytes abnormality. Results: The Mean level of TC, TG, LDL, Potassium and Chloride were significantly higher in HDM as compared with NDM. While, level of HDL-C and Sodium had a significantly lower in HDM as compared to HDM. In binary logistic regression: Hypertension, BMI, WC and DM showed strong significant association with abnormal serum level of TG, TC, LDL-C, HDL-C and Sodium in HDM than NDM. Conclusion and Recommendation: HDM have more chances to develop high dyslipidemia and electrolytes disturbance than NDM. Hypertension, BMI, WC and DDM were factors significantly associated with abnormal lipid profiles and electrolytes level among HDM than NDM. There should be regular monitoring of lipid profile, electrolytes and hypertension for diabetic patients to prevent diabetes related complications.