Browsing by Author "Gudeta, Hoffola"

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    Assesment of Magnitude and Associated Factors of Neonatal Hyperbilirubinemia at Neonatal Intensive Care Unit of Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia, 2017
    (Addis Ababa University, 2017-06) Gudeta, Hoffola; Mengistu, Zuriyash (PhD)
    Background: Neonatal hyperbilirbinemia (NH) is a recognized cause of brain damage and bilirubin encephalopathy resulting in long-term sequel like sensory-neuronal hearing loss in the survivors and death. Objective: To assess magnitude and associated factors of NH among neonates admitted at neonatal NICU from September 11/2014 to September 11/2016 in TASH. Methodology: Retrospective cross sectional study was conducted on neonates admitted at NICU of TASH and 356 neonates were systematically selected among all admitted neonates. Study was conducted from January 2017 to June 2017. Supervisors and data collectors were BSc health professionals. Pre-test was conducted on 5% of sample before the starting of actual data collection. Checklist was adopted and modified from literatures to collect data. Supervisors were checked the collected data daily for completeness. Data was first entered to Epi Info version 7 and exported to SPSS version 20.0 to clean and analyze data. Relation between dependent and independent variables were assessed and presented using odd ratios and confidence intervals. Statistical association was considered as significant if p-value was less than 0.05. Ethical clearance for the study was received from Addis Ababa University, College of Health Sciences. A formal letter was written to TASH and permission was secured at all levels. Result: Medical record of 356 neonates were reviewed and 160(44.9%) of them developed NH. 89(25%) of males and 71(19.9%) of females were developed neonatal hyperbilirubinemia. Their serum bilirubin level was from 5.6mg/dl to 77.7mg/dl. Among associated factors of NH: ABO incompatibility 57(35.6%), sepsis 30(18.8%), idiopathic cause 22(13.8%), breast feeding jaundice 16(10%) and Rh isoimmunization 14(8.8%). Age of neonates was significantly associated with neonatal hyperbilirubinemia in logistic regression. Conclusion and Recommendation: Magnitude of neonatal hyperbilirubinemia in this study was near to half of selected neonates. Among identified associated factors of NH, ABO incompatibility and sepsis were the leading cause. So, early prevention and timely treatment of NH is important since it was a cause of long term complication and death in neonates. Keyword: Magnitude, Neonatal hyperbilirubinemia