Browsing by Author "Gedefaw Tigabu"

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    Practice of Informed Consent and Associated Factors Influencing its Application in Emergency Department Among, Residents and Nurse
    (Addis Ababa Universtity, 2025) Wondim Aboye; Gedefaw Tigabu; Finot Debebe
    Informed consent is a basic principle for the ethical and legal conduct of healthcare that protects the autonomy of the patient. At present, its practice in the emergency departments (EDs) is hindered by time pressure, lack of patient education, patient ignorance, and emotional distress, notably in low middle income states, such as Ethiopia. Objective: The study aims to is to assess informed consent practice and associated factors influencing its application in emergency departments among residents and nurses of selected governmental hospitals in Addis Ababa Methods: A cross-sectional institutional study was conducted on nurses and residents from three tertiary hospitals, namely Tikur Anbessa Specialized Hospital (TASH), Saint Paul’s Hospital Millenium Medical College (SPHMMC) and Yekatit 12 Medical College. Data were collected on self-administered Google Form, and analyzed using SPSS 27. For multivariate analysis, variables with binary logistic regression (p < 0.25) were used, accounting for potentially confounding factors. Results: Among 157 residents and nurses, 144 were included in this study and 51.8% have good informed consent practice. Residents and nurses with good knowledge about informed consent [AOR: 7.17 (95%CI: 2.267-22.682)], regular supervision from administration [AOR: 4.72 (95%CI: 1.706-13.06)], consideration of patients' cultural norms [AOR: 2.911 (95% CI: 1.024-8.278)] and patients’ incapacity to make decisions [AOR: 0.242 (95% CI: 0.089-0.657)] were significantly associated with informed consent practices. Conclusion: Good informed consent, driven by professional knowledge, administrative oversight, and cultural norms yet challenged by patients’ incapacity to make decisions, can be enhanced through continuous education, robust administrative support, cultural competency training, and clear protocols.
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    Research Practice and Associated Factors Among Emergency and Critical Care Medicine Residents In Ethiopia
    (Addis Ababa University, 2024-01-15) Gedefaw Tigabu; Tigist Worku
    Outside the required academic research, very little and no research practice involvement has been determined. There is a paucity of knowledge regarding research practices in Emergency Medicine residents in Ethiopia, which calls for further research and analysis.
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    The Prognostic Value of Neutrophil to Lymphocyte Ratio in Sespsis among Adult Emergency Patients at Tikur Anbessa Specialized Hospital (TASH) And Zewditu Memorial Hospital (ZMH) , Addis Ababa, Ethiopia
    (Addis Ababa University, 2025-12-12) Awetahegn Ephrem; Birhanu Tesfaye; Gedefaw Tigabu
    Background: - Sepsis Is Life-Threatening Condition Resulting from a Deregulated Immune Response to Infection with High Morbidity and Mortality Particularly in Low- And Middle-Income Countries Such as Ethiopia. The Significant Burden of Sepsis in Ethiopian Emergency Departments Underscores the Need for Improved Diagnostic Tools and Treatment Strategies. The Neutrophil-To Lymphocyte Ratio (NLR) Has Emerged as a Promising Biomarker That May Predict Clinical Outcomes in Sepsis, Yet Its Utility Is Ethiopian Context Remains Unexplored. Objective: - The Prognostic Value of Neutrophil to Lymphocyte Ratio in Sepsis Among Adult Emergency Patients at Tikur Anbessa Specialized Hospital (TASH) Addis Ababa and Zewditu Memorial Hospital (ZMH), Ethiopia Multicenter Prospective Cross-Sectional Study Methods: - The Study Was Conducted at TASH & ZMH In the Emergency Department. The Research Design Used for This Study Is Institutional-Based Prospective Cross-Sectional Study Design, Which Involves Collecting Data at Over 3 Months Period from Selected Sepsis Patients After Diagnosis by SOFA Guideline Admitted at the Emergency. The Data Were Collected from Aug 15- November 30, 2025, Through A Standard Checklist and Laboratory Results by a Data Collector. Results: Among The Study Population, 58% Recovered While 42% Died. Non-Survivors Had Higher WBC Counts, Neutrophil Percentages, And Markedly Elevated NLR At Admission (24.52) Compared to Survivors (14.1). NLR After Treatment Remained Significantly Higher in Non-Survivors (28.99 Vs. 11.46). ROC Analysis Showed That NLR Had a Moderate Predictive Accuracy with an AUC Of 0.713 (95% CI: 0.618–0.808; P=0.000). Conclusion: The Findings Align with Extensive Literature (21–30) Showing That Elevated NLR Is Consistently Associated with Poor Prognosis, Severity, And Increased Risk of Death. Routine NLR Monitoring May Enhance Early Risk Stratification and Guide Timely Clinical Interventions in Sepsis Care. Work Plan – The Total Research Work from Title Selection to Presentation Was Completed In 6 Months