Browsing by Author "Gedefa, Bikila"

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    Prevalence of Neurocognitive Impairment and Associated Factors among Type-2 Diabetic Patients on Follow Up at Diabetic Clinic, Tikur anbessa Specialized Hospital, Addis Ababa, Ethiopia
    (Addis Ababa University, 2021-12) Gedefa, Bikila; Tarekegn, Getahun (MD, Consultant Internist and Endocrinologist)
    Background:-Neurocognitive disorders in patients with type 2 Diabetes Mellitus has spectrum manifestation which might range from subtle executive dysfunction to memory loss and overt dementia. Diabetes patients are at higher risk of all types of cognitive impairment, mainly because some diabetes complications results in cognitive impairments and they are also being considered as disease of the same spectrum. Even though it is estimated that more than 50 million peoples live with dementia worldwide, there is no enough data from low and middle income countries, including Ethiopia, where the number is projected to increase to 152 million by 2050. Hence this study will focus on assessing the overall prevalence, potential determinant and contributing factors among patients with type 2 DM over a period of two months at Black Lion Specialized Hospital, Ethiopia. Objective: - To assess the neurocognitive impairment and associated factors among diabetic patients on follow up at diabetic clinic, Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia from July 1- August 30, 2021 Methods A hospital based Cross-sectional study was conducted on total of 338 type 2 diabetic patients on follow-up at BLH. The sociodemographic, anthropometric and clinical data was collected by trained final year medical students. Both face to face interview and medical record reviews were used for data collection. A validated Mini Mental Status Examination tool was used to assess cognitive impairment. Data was entered to epi-data cleared and analyzed by SPSS version 26.0. Finally, Descriptive analysis was carried out and presence of statistical association between neuro-cognitive impairment and associated factors was assessed using logistic regression and associations with p-value of < 0.05 will be considered to be statistically significant. Results The overall prevalence of neurocognitive impairment among type 2 diabetic patients on follow up at black lion specialized hospital was 38.75%. From Socio-demographic factors low educational level [AOR=3.65(1.855-7.188)] was associated with increased odds of encountering cognitive impairments. While some clinical characteristics like being on oral hypoglycemic agents [AOR=0.786 (0.370-1.669)] or oral hypoglycemic agents combined with insulin [AOR=1.87(1.054-4.264) were associated with decreased likelihood of cognitive impairments. Total duration of DM [(AOR=1.95(0.987-3.877)] and overall glycemic control [AOR= 2.21(1.238-3.947)] had significant association with NCI. additionally coexisting hypertension [AOR= 0.53(0.314-0.918)] and presence of diabetic eye disease [AOR=1.84(1.056-3.229)] were also associated with increased odds of encountering impairment. Conclusion: - The finding indicated high prevalence of neurocognitive impairment among respondents who had low level of education, prolonged duration of DM, poorly controlled DM, diabetic eye disease and coexisting hypertension.