Browsing by Author "Birku Gashaw"

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    Assessment of Liver and Renal Function Tests among Patients with Typhoid Fever in Motta General Hospital, Northwest Ethiopia
    (Addis Ababa University, 2024-07-15) Birku Gashaw; Samuel Kinde
    Typhoid fever is a systemic infection caused by salmonella typhi. Oro-fecal contamination is a common route of entry to cause infection of the gastrointestinal system. The bacteria then burrow the walls of the intestines and cause bacteremia through a profusion of bacteria in a person’s bloodstream, which invade the liver, kidney, and other organs. In addition to the systemic infection, the liver organ can exposed to the bacteria directly via the gut-liver axis (enterohepatic circulation). Typhoid hepatitis and renal damage are the atypical presentations of typhoid fever. Lack of sensitive and specific diagnosis tests leads to poor clinical management of typhoid fever