Browsing by Author "Berihun,Asrat"

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    Assessment of Health-Related Quality of Life in Patients with Inflammatory Bowel Disease at Tikur Anbessa Specialized Hospital, Ethiopia
    (Addis Ababa University, 2024-02) Berihun,Asrat; Mohammed,Duelsome(MD)
    Introduction: Inflammatory bowel diseases are chronic progressive/relapsing conditions that affect the younger population and have been associated with reduced health-related quality of life. HRQOL is an important outcome measure in IBD and helps to understand impact of the disease on the patient and the effect of treatment on the disease. Aim: To assess health-related quality of life in IBD patients and associated socio-demographic and clinical factors. Methods: A hospital-based cross-sectional study using the "Short Inflammatory Bowel Disease Questionnaire" (SIBDQ) was conducted in Tikur Anbessa Special Hospital from September 1, 2023 to December 30, 2023. Data were entered and analyzed using SPSS version 27. Descriptive statistics were used to show frequencies and percentages. A binary logistic regression model was used to assess predictors of impaired HRQOL in patients with IBD. Strength of association is measured by AOR and 95% CI. Variables with a P-value < 0.05 have a statistically significant association. Results: Thirty-one percent of IBD patients in our study had impaired HRQOL (SIBDQ<50) with no statistically significant difference between IBD types, gender, marital status, residence, surgical treatment and duration of IBD. Unemployment (AOR= 4.36; CI 95%:1.34-14.18; p=0.014), not being in remission (AOR= 14.62; CI 95%: 2.31-92.53; p= 0.004), comorbidity (AOR= 9.18 ;CI 95%: 2.24-37.69, p=0.002), admission (AOR= 5.08; CI 95%: 1.45-17.76, p=0.011) and symptom duration > 6 months before diagnosis (AOR= 4.679; CI 95%: 1.31-16.74; P=0.018) were significantly associated with impaired HRQOL. Conclusion: In our study, about one in three of IBD patients had impaired HRQOL. HRQOL was better with controlled disease activity; no hospitalization, no EIMs, and no comorbidity; early diagnosis, employment, and higher educational level.