Browsing by Author "Asrat, Asmamaw"

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    Dynamics of Motor Proteins a Monte Carlo Simulation
    (Addis Ababa University, 2011-07) Asrat, Asmamaw; Yergou, Tatek (PhD)
    Motor proteins are mechanochemical enzymes that convert energy released by adenosine triphosphate (ATP) hydrolysis into either linear or rotary movement. Motor proteins: kinesin, myosin and dynein, that perform active movements along cytoskeletal laments drive the long=range transport of vesicles, organelles, and other types of cargo in biological cells. In this Monte Carlo simulation study, based on the recent experimental results and existing theoretical models, a lattice model to study the dynamics of non=interacting motor proteins each transporting a cargo and a new bead=spring model to study the collective dynamics of interacting motor proteins transporting cooperatively a common cargo are proposed and studied