Dynamics of Motor Proteins a Monte Carlo Simulation
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Date
2011-07
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Addis Ababa University
Abstract
Motor proteins are mechanochemical enzymes that convert energy released by adenosine
triphosphate (ATP) hydrolysis into either linear or rotary movement. Motor proteins:
kinesin, myosin and dynein, that perform active movements along cytoskeletal laments
drive the long=range transport of vesicles, organelles, and other types of cargo in biological
cells. In this Monte Carlo simulation study, based on the recent experimental results and
existing theoretical models, a lattice model to study the dynamics of non=interacting
motor proteins each transporting a cargo and a new bead=spring model to study the
collective dynamics of interacting motor proteins transporting cooperatively a common
cargo are proposed and studied
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Keywords
Dynamics of Motor Proteins