Browsing by Author "Alemu, Jemal(MSc)"

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    Establishment of hematological parameters reference intervals for apparently healthy adolescents in Asella town, South East Ethiopia
    (Addis Abeba University, 2020-06) Dibaba, Berhanu; Tsegaye, Aster (MSc, PhD); Alemu, Jemal(MSc)
    Background: -Physicians' medical decisions are based on information provided by laboratory reports in the form of a reference interval (RI) or medical decision limit. The interval serves as a health-related standard with which to compare an individual test result. However, the lack of bringing up as its own standard, local reference values has been a problem facing hematological practice in our country. Objective: To establish hematological parameters reference intervals for apparently healthy adolescents (12-17) in Asella town, South East Ethiopia from January to March 2020 GC. Method: A total of 342 apparently healthy adolescents aged 12–17 years living in Asella town and fulfilling the eligibility criteria were recruited for this cross-sectional descriptive study using a systematic random sampling method. Data including socio-demographic characteristics were collected using a structured questionnaire. The hematological analysis was performed using Sysmex KX-21 3 Diff analyzer. Data was entered and analyzed using SPSS version 21. The nonparametric Mann-Whitney u test was used to compare the parameters between genders. The 97.5 percentile and 2.5 th percentile as the upper and Lower Reference limit in favor of the adolescent population were determined. Result: The study observed statistically significant mean differences between males and females in Hemoglobin (HGB), Hematocrit (HCT), Mean cell hemoglobin concentration (MCHC), Mean Cell volume (MCV), absolute lymphocyte number (LYM#), Red Blood Cell (RBC), and Red blood cell distribution width by the coefficient of variation (RDWCV). Whereas the mean values of other Hematological parameters like WBC PLT and RWDSD have no significant difference between both sex (p value>0.05). Hence the reference interval of White Blood Cells (WBC), Platelet (PLT) and Red blood cell distribution width by the standard deviation (RWDSD) in adolescents were (3.410. 9x103/ul), (153.9-390x103/ul) and (36.8-47.1fl) respectively. The current established reference intervals show higher proportions out of range values when compared to the existing reference intervals. Conclusion: Some hematological parameter showed a significant difference in the mean values among data sets for HGB, RBC, MCV and MCHC across gender (p value<0.05) in which females having lower levels than males. The newly established hematological parameter reference intervals by this study were different from the existing reference values. th
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    Magnitude of Anemia and Associated Factors in Children Aged 6-59 Months at Keranyo Health Center, Addis Ababa, Ethiopia
    (Addis Abeba University, 2021-02) Jiru, Zewdu; Tsegaye, Aster(MSc, PhD); Alemu, Jemal(MSc)
    Background: Anemia impairs physical capacity and work performance in all age groups. In children, anemia affects cognitive and motor development because of the need for adequate oxygen carrying capacity during the critical first few years of life when mental and physical growth are occurring at their fastest. In Ethiopia, Anemia among children aged 6-59 months children categorized as severe public health problem. Regular monitoring of the magnitude anemia and its predicting factors is helpful for appropriate intervention. Objective: To assess the magnitude of anemia and associated factors in children aged 6-59 months at Keranyo health center, Addis Ababa, Ethiopiafrom January 01 to February 30, 2020. Method: A cross sectional health facility based study wasconducted among 427 children aged 6 to 59 months. Convenient sampling technique was used to include the participants. Pretested and structured questionnaire was used to collect socioeconomic and demographic characteristics of the family and child. Data on nutritional status and capillary blood sample was collected from each child. Multivariate logistic regression was used to calculate adjusted odds ratios with the corresponding 95% confidence intervals.P-values less than 0.05 was also used to declare statistical significance. Result: Of the total 427 children, 210 (49.2%) were males. The overall prevalence of anemia among children aged 6-59 months was 177(41.5%) (95% CI: 36.8% - 45.9%). Of the anemic under-five children, 14(3.3%) had mild, 149(34.9%) moderate and 14(3.3%) had severe anemia. Children whose maternal education is below elementary((AOR=3.82, 95% CI = (1.66, 8.77)), children who had fever in the last 2 weeks (AOR=2.13; 95% CI: (1.33, 3.42)), who consumed tea (AOR=2.17; 95% CI: (1.20, 3.93)) and with mothers who was not supplemented with iron during their last pregnancy (AOR=3.02; 95% CI: (1.40-6.55)) were more likely to become anemic. Conclusion: This study confirmed thatthemagnitude of anemia in children aged 6-59 months in Keranyo health centeris in the severe public health category. Educational and occupational status of the mother, child history of fever in the last two weeks, child tea consumption and maternal iron supplementation during pregnancy were factors associated with anemia in those children (659 months).Therefore, strengthening awareness and bringingbehavioural change in order to increase the knowledge of reproductive women about anemia is warranted.