Surgery

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Browsing Surgery by Author "Abel(Dr.)"

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    Proposal on Incidence and Predictors of Surgery Related Cerebro- Vascular Ischemic Complications among Patients Undergoing Cranial Neuro-OncologicProcedures: Multi- Centric Prospective Observational Study.
    (Addis Ababa University, 2023-05) Yibeltal,Mestet; Abat(Dr.); Abel(Dr.)
    Background: Surgical management of brain tumors while proved to be the single most effective therapeutic armamentarium; it is not however free of some dreadful complications like cerebrovascular ischemic complications. These ischemic cerebrovascular complications are separate entities of variable severity of basically the same problem; an ischemic vascular problem ultimately resulting cerebral infarction and /stroke with significant morbidity and mortality to the patients. This surgery related cerebrovascular problem comprises of a spectrum of disease entities that includes cerebral vasospasm, delayed cerebral ischemia (DCI), vascular thrombosis, pseudoaneurysms, direct iatrogenic vascular injuries and ischemic &/embolic strokes with different diagnostic modalities, therapeutic options and outcome. Objective: The main objective of this study will be assessing the incidence and predictors of surgery related cerebro-vascular ischemic complications among patients undergoing brain tumor resection at BLH & MCM from April 1-September 30; for 6 months. In addition, this study will also be developing a risk prediction model for the prediction of cerebral vascular ischemic complications among the study subjects. Methodology: A hospital based prospective observational cohort follow-up study will be conducted starting from April 1-September 30 for the occurrence of ischemic cerebral vascular complications among patients who underwent cranial surgery for brain tumor resection. The study outcome will be assessed in patients who underwent brain tumor surgery at the immediate postop, 3-4th post op day, 7-8th post op day, 12-14th post op day and 30th postop day based on a set of diagnostic criteria and operational definition set. Univariate & bivariable analysis will be done to see the association of each predictor variable with cerebral vascular ischemic complication. Variables with p-value of <0.25 in the bivariable analysis will be entered to multivariable analysis. The statistical significance will be declared at p-value <0.05. The measure of association will be Risk Ratio (RR) with 95% confidence interval. The risk prediction model will also be presented in the form of nomogram. Conclusion: post cranial tumor resection cerebrovascular ischemic complications are grave complications that have immense implication to the patient’s overall functional outcome. Hence, this problem warrants study.