Radiology
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Browsing Radiology by Author "Alwan, Amir (MD, Assistant Professor of Radiology)"
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Item A Cross sectional study of Chest metastasis patterns of all malignancies presented to radiology department at Tikur Anbesa Specialized Hospital, Addis Ababa University, Addis Ababa, Ethiopia from October 2018 – May 2019.(Addis Abeba University, 2019-10) Mulugeta, Sofia; Gissila, Azmera(MD, Assistant Professor of Radiology); Alwan, Amir (MD, Assistant Professor of Radiology)Back ground: Chest is one of the commonest metastasis site of the thoracic or extra thoracic malignancies and Pulmonary metastases have widely variable presentation on imaging and may simulate primary lung tumor or nonmalignant diseases. Therefore, it is important for the radiologist to be familiar with the full spectrum of findings to facilitate correct diagnosis and this study has tried to look for the pattern of chest metastasis. Objective: This study aimed to assess the overall chest metastasis patterns of both thoracic and extra thoracic malignancies and their possible histologic correlation. Methods: A prospective cross sectional study of 202 patients was done from October 2018- May 2019. A structured questionnaire was used to collect data for analysis. Results: of the total 202 cases there are 25 primary sites and the majorities come from the following sites in the descending order esophagus (63), breast (47), lung (24), bones (14), soft tissues (10), thyroid (9), head and neck (11) and miscellaneous (24). The commonly seen histologic variant is Squamous cell carcinoma (46 cases); majority from the esophagus followed by Adenocarcinoma (26 case); majority from the breast and the lung followed by sarcomas (24 cases) mainly from the bones and soft tissues and other miscellaneous histologic variants account 16cases from different sources. For the rest of cases the histology is not known. The commonest metastatic site is found to be the lung parenchyma and air ways (accounting 120 cases with multinodular pattern being the commonest (67cases). The second is found to be the mediastinum accounting 108 cases mainly involving the lymph nodes (106 cases). The 3 the pleura (58 cases) with the pleural nodule being the predominant pattern (24 cases). The last is chest wall metastasis accounting for 53 cases mainly involving the bones (26 cases). There is statistically significant positive correlation seen between the calcific metastasis and sarcomas but no statistically significant correlation between other histologic types and lung metastasis pattern. Conclusion: In both thoracic and extra thoracic malignancies lung parenchymal and air way metastasis is the commonest with multinodular pattern followed by lymphatic spread. The others 2 rd site is are mediastinal, pleural and chest wall metastasis respectively. Calcific metastasis has significant positive correlation with sarcomas.Item Cross Sectional Study of Unsuspected Pulmonary Embolism in Oncology Patients Undergoing Chest Computed Tomography Imaging in Tikur Anbessa Specialized Hospital Addis Abeba University, Addis Abeba ,Ethiopia.(Addis Abeba University, 2019-09) Alemayehu, Tesfaye; Gissila, Azmera(MD, Assistant Professor of Radiology); Alwan, Amir (MD, Assistant Professor of Radiology)Background Oncology patients have a fourfold higher risk for developing pulmonary embolism than that of the general population. Acute pulmonary embolism (PE) is a common and often fatal disease. Furthermore, most cases of PE that eventuallycause fatality are clinically unsuspected and therefore go untreated. Finding of incidental PE in oncologic patients significantly affects management and prognosis of patients. Diagnosis of PE leads to start of therapeutic anticoagulation and prevents embolic recurrence that is associated with substantial morbidity and mortality. A lthough the MDCT protocol for CT pulmonary angiography differs from that used for routine chest CT, modern CT systems, along with high-concentration contrast media, enable detection of pulmonary emboli even in routine chest CT, increasing the frequencyof detection of clinically unsuspected pulmonary embolism. 2 Objective This study is designed to assess prevalence of incidentalpulmonary embolism in oncologic patients detected by chest computed tomography. Method Hospital based prospectivecross-sectional study conducted at TASH to address the specific objective during the study period (July, 2018-January 2019 G.C).This study was conducted among oncologic patients being evaluated at TikurAnbessa Specialized Hospital who have chest CT imaging during the study period. Chest CT was evaluated for the presence of abnormalities. The study population included all oncologic patients having chest CT imaging during the data collection period. Data was collected by evaluating the CT by radiologist. The data was checked for clarity and completeness. Computerized data analysis was conducted by using SPSS version 20.0 software. RESULT The prevalence of incidental PE was 1.7% in this study. A total of 10 patients out of 573 patients had incidental PE. The most common primary malignancy was GIT malignancy (30.9%). The other malignancies were hematologic malignancies among 12.9%, breast cancer in 12.6%, and cancers of the genitourinary tract in 7.7%. the rest of patients had varieties of different cancer types.80% of the patients with PE had multiple PE and 20% had single PE. The most commonly involved part of the lung was RLL which was involved in all cases of incidental PE. Followed by LLL which was involved in 60%. In general, the upper lobes and the RML were involved in 40% of the cases, each. All cases of single PE occurred in the RLL. 3 The most frequently involved divisions of the pulmonary were the lobar branches in 80% of the PE cases followed by segmental branches (70%). The main division was involved in 40% of the cases, while the subsegmental division was involved in none of the cases. Limitation of the study -Lack of good pulmonary arterial opacification and motion artifacts which can limit detection of PE. -Lack of properly handled patient’s chart. -Limited sample size. CONCLUSION The prevalence of incidental PE detected on routine chest CT scan is 1.7% with no detected small artery PE. The risk of incidental PE was higher in older age and advanced malignancy. The diagnosis of incidental PE has significantly changed the management in all of these patients. Good pulmonary arterial contrastopacificationis required for diagnosis.