Insulin Induced Lipohypertrophy and Glycemic Control among Children and Adolescents with Diabetes in Tikur Anbesa Specialized Hospital, Addis Ababa, Ethiopia
| dc.contributor.advisor | Shibeshi, Workineh (PhD, Associate professor) | |
| dc.contributor.author | Gebremeskel, Afewerki | |
| dc.date.accessioned | 2018-10-22T08:00:52Z | |
| dc.date.accessioned | 2023-11-29T04:30:29Z | |
| dc.date.available | 2018-10-22T08:00:52Z | |
| dc.date.available | 2023-11-29T04:30:29Z | |
| dc.date.issued | 2017-12 | |
| dc.description.abstract | Insulin Induced Lipohypertrophy and Glycemic Control among Children and Adolescents with Diabetes in Tikur Anbesa Specialized Hospital, Addis Ababa, Ethiopia Afewerki Gebremeskel Addis Ababa University, 2017 Lipohypertrophy (LH) is one of the clinical complications of insulin injection which affects insulin absorption and leads to poor glycemic control. Its occurrence was mainly associated with the use of non-human origins of insulin and repeated traumatization of injection sites. Aim of this study was to assess insulin induced LH and glycemic control among children and adolescent patients from April to July 2017 in Tikur Anbesa Specialized Hospital, Addis Ababa, Ethiopia. This cross sectional study was done on 176 diabetic children and adolescents who inject insulin for a minimum of one year. First, the anthropometric and clinical features of the patients were recorded in questionnaire and then observation and palpation techniques were used in assessing LH. Out of the total 176 participants, 103 (58.5%) had insulin induced LH, of them 3 (2.9%) had lipoatrophy. Factors such as age, weight, height and insulin syringe reuse had significant influence in development of insulin induced LH, considering p-value <0.05 as significant level. LH in turn was associated with the use of higher dose of insulin and non-optimal glycemic control. Overall, some insulin injection malpractices have been found among participants of this study. As a result injection site uncleaning was significantly associated with the occurrence of non-optimal glycemic control. Findings of this study revealed that inspite of using recombinant human insulin, the magnitude of the LH still remained high. Therefore, a regular examination of the diabetic patients for this complication is necessary, especially in the individuals who have a defective glycemic control. | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/123456789/13040 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Addis Ababa Universty | en_US |
| dc.subject | Diabetes mellitus, Insulin, Lipohypertrophy, Lipodystrophy, Glycemic control, Tikur Anbesa Specialized Hospital, Ethiopia | en_US |
| dc.title | Insulin Induced Lipohypertrophy and Glycemic Control among Children and Adolescents with Diabetes in Tikur Anbesa Specialized Hospital, Addis Ababa, Ethiopia | en_US |
| dc.type | Thesis | en_US |