Prevalence and Type of Anaemia Due to Hookworm Infection Among the Populations of Wolisso
| dc.contributor.advisor | Mekonnen, Yalemtsehay (PhD) | |
| dc.contributor.author | Tsegaye, Aster | |
| dc.date.accessioned | 2018-06-21T12:40:18Z | |
| dc.date.accessioned | 2023-11-08T16:33:58Z | |
| dc.date.available | 2018-06-21T12:40:18Z | |
| dc.date.available | 2023-11-08T16:33:58Z | |
| dc.date.issued | 1995-06 | |
| dc.description.abstract | A community based case-control study to investigate the relationship between hookworm infection and anaemia was carried out on 227 apparently healthy individuals living around Wolisso area. Of these subjects 155 were cases (individuals infected with hookworm) and 72 were controls (uninfected). It was found that 20.6% of the cases and 5.6% of the controls were anaemic. Chi-squared analysis showed hookworm infection was significantly associated with low haemoglobin (odds ratio = 4.42, P<O.05),10w transferrin saturation (odds ratio = 17.18, P<O.OOl) and low ferritin levels (odds ratio = 14.98, P<O.Ol). Intensity of infection as expressed in eggs per gram (epg) of faeces showed a highly significant negative relationship with transferrin saturation and serum ferritin levels (P<O.OOl) but not with haemoglobin levels (P>0.05). When multiple criteria involving elevated mean corpuscular volume (~fCV), mean corpuscular haemoglobin (MCH) and macrocytic blood picture were taken as suggestive of a macrocytic type of anaemia, 13.0% of the cases and 5.6 % of the controls fell into this category. Chi-squared analysis however, showed no statistically significant association between parameters suggestive of macrocytic anaemia and hookworm infection (odds ratio = 2.54, P>0.05). Further investigation is recommended to clearly indicate the role of hookworms in the genesis of megaloblastic anaemja by employing better biochemical assays. The intensity of infection was light and the anaemia was generally of mild type. | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/123456789/2731 | |
| dc.language.iso | en | en_US |
| dc.publisher | Addis Ababa University | en_US |
| dc.subject | Biology | en_US |
| dc.title | Prevalence and Type of Anaemia Due to Hookworm Infection Among the Populations of Wolisso | en_US |
| dc.type | Thesis | en_US |