Phytochemical Investigation on the Leaves of Achyranthes Aspera
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Date
2013-10-10
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Addis Ababa University
Abstract
Achyranthes aspera is a well known medicinal plant in the family Amaranthaceae. The plant is
locally known as “Telenge”. It is traditionally used in asthma and cough. The root of
Achyranthes aspera is used for anti snake bite by giving the ground root with water until the
patient vomits and regains consciousness while the crushed leaves are used to cure strained back.
Phytochemical investigation on the leaves of this plant resulted in the isolation of two
compounds (AA-1and AA-2). Compound AA-1 is a sesquiterpene while compound AA-2 is an
insect molting ecdysteroid hormone namely:
1.) 4,4a,7,8-tetrahydro-4-hydroxy-4a,7,8-trimethyl-8-(tetrahydro-3,4,5-trihydroxy-6-
(hydroxymethyl)-2H-pyran-2-yloxy)naphthalen-2(3H)-one
2.) 20-hydroxyecdysone.
Structural elucidations of those compounds are based on IR, UV, 1D NMR (1H, 13C &DEPT) and
2D NMR (COSY, HMQC &HMBC) spectroscopic data obtained and in comparison with similar
compounds isolated from the plant.
To the best of my knowledge, there is no report for the isolation of the first compound (AA-1)
from this plant and other families and species.
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Keywords
Phytochemical, Investigation, Leaves, Achyranthes, Aspera