Preliminary Phytochemical Investigation of the Root of Verbascum Sinaiticum (Scrophulariaceae)
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Date
2024-08
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Addis Ababa University
Abstract
The focus of this study was preliminary phytochemical investigation of the methanol extracts of
the root of V. sinaiticum (Scrophulaceae). The plant is traditionally used in Ethiopia for various
medicinal purposes including wound healing anti-microbial activities. The extraction and
characterization of bioactive compounds were conducted using a Cyclohexane: ethyl acetate (2:1)
solvent system. The extracts were then analyzed using various spectroscopic methods such as TLC,
1 H-NMR, 13 C NMR and DEPT-135, to elucidate the structural characteristics of the isolated
compounds. The isolated compound from the root extract was identified as 9, 12, 15-
octadecatrienoic acid or α-linolenic acid (ALA), an essential omega-3 fatty acid known for its
potential health benefits. ALA has been linked to various health advantages, including
cardiovascular health, diabetes management, renal health, and anti-inflammatory properties.
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Keywords
Verbascum Sinaiticum, Phytochemical Composition, Α-Linolenic Acid, Omega-3 Fatty Acid, Traditional Medicine, Health Benefits, and Acetone-D6