Preliminary Phytochemical Investigation of the Root of Verbascum Sinaiticum (Scrophulariaceae)

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Date

2024-08

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Addis Ababa University

Abstract

The focus of this study was preliminary phytochemical investigation of the methanol extracts ofthe root of V. sinaiticum (Scrophulaceae). The plant is traditionally used in Ethiopia for variousmedicinal purposes including wound healing anti-microbial activities. The extraction andcharacterization of bioactive compounds were conducted using a Cyclohexane: ethyl acetate (2:1)solvent system. The extracts were then analyzed using various spectroscopic methods such as TLC,1 H-NMR, 13 C NMR and DEPT-135, to elucidate the structural characteristics of the isolatedcompounds. The isolated compound from the root extract was identified as 9, 12, 15-octadecatrienoic acid or α-linolenic acid (ALA), an essential omega-3 fatty acid known for itspotential health benefits. ALA has been linked to various health advantages, includingcardiovascular health, diabetes management, renal health, and anti-inflammatory properties.

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Verbascum Sinaiticum Phytochemical Composition Α-Linolenic Acid Omega-3 Fatty Acid Traditional Medicine Health Benefits and Acetone-D6

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