Assessment of Drug Therapy Problems and Contributing Factors among Adult Ambulatory Hypertensive Patients in Ayder Referral Hospital, Mekelle Northern Ethiopia: A cross sectional study

dc.contributor.advisorShibeshi, Workineh(PhD)
dc.contributor.advisorFeyissa, Mamo
dc.contributor.authorMahammedsied, Werkya
dc.date.accessioned2020-03-13T02:22:42Z
dc.date.accessioned2023-11-29T04:30:30Z
dc.date.available2020-03-13T02:22:42Z
dc.date.available2023-11-29T04:30:30Z
dc.date.issued2019-02
dc.description.abstractHypertensive patients are at high risk of Drug therapy problems (DTPs) as they often received multiple medications in order to achieve their target blood pressure. Currently studies concerning DTPs in patients with hypertension are limited in Ethiopia. Therefore, this study was aimed to assess the magnitude of DTPs and contributing factors among adult ambulatory hypertensive patients in Ayder referral Hospital. Institution based cross sectional study was conducted among 384 study subjects who fulfilled the inclusion criteria. Trained data collectors collected the data from patient interview and chart review using structured data collection format. DTPs were assessed using Cipolleā€˜s classification system. Logistic and multivariate regression analysis was performed to identify factors associated with DTPs. Data were reported as mean and percentage using tables and figures. DTPs were found in 52.8% of study subjects. A total of 277 DTPs were identified from 203 study subjects in which, 1 DTP was identified from 133(65.5%) patients, 2 in 66 (32.5%) patients and 3 in 4(1.97%) patients. The maximum number of DTPs found was 3 and the average number of DTPs per patient was 1.36. Unnecessary drug therapy was the top leading (32.5%) and dose too low (7.94%) was the least type of DTPs in the study subjects.ACEIs were the most frequent drugs involved in DTPs.The factor that was independently associated with DTPs was the total number of medications. The total number of medications taken by the patient per day was an important predictor of drug therapy problem AOR = 2.572 95% CI (1.062-6.229), P=0.01.en_US
dc.identifier.urihttp://etd.aau.edu.et/handle/123456789/21151
dc.language.isoen_USen_US
dc.publisherAddis Ababa Universityen_US
dc.subjectDrug therapy problems, hypertension, Ambulatory, Mekelle, Ethiopiaen_US
dc.titleAssessment of Drug Therapy Problems and Contributing Factors among Adult Ambulatory Hypertensive Patients in Ayder Referral Hospital, Mekelle Northern Ethiopia: A cross sectional studyen_US
dc.typeThesisen_US

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