Level of Adherence and Associated Factors to Option B+ Pmtct Programme Among Pregnant & Lactating Mothers in Selected Government Health Facilities of South Wollo Zone, Amhara Region, North East Ethiopia, 2016
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Date
2016-06
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Addis Ababa University
Abstract
Introduction፡ Adherence to ART among HIV positive pregnant & lactating mothers is a
central component in PMTCT to reduce viral loads & achieve elimination of mother to child
transmission of HIV. Option B+ PMTCT programme is a recently introduced approach to
eliminate new HIV infection among children. This approach is based on treatment as
prevention to mean starting lifelong ART for all HIV positive pregnant & lactating mothers
without considering CD4 count or clinical stage of HIV/AIDS disease.
Objectives: The aim of this study was to measure the level of adherence and identify factors
associated with adherence to option B+ PMTCT programme among pregnant & lactating mothers
in selected government health facilities of south wollo zone, Amhara region, north east Ethiopia
Method: An institution based cross sectional quantitative study design was used. The study was
conducted in two hospitals & five health centers found in south Wollo zone, Amhara region. The
sample size required for this study was 191 HIV+ pregnant & lactating mothers who were on
PMTCT follow up. The study subjects were taken consecutively until the sample size was met
from March 1 to April 14, 2016. Standard structured data collection instrument was used & it
was collected by using face to face interviewing. The data were entered in to EpiData 3.1 then
exported to statistical package for social science (SPSS) window version 21 for analysis. Entered
data were explored for errors & missing values then it was cleaned before analysis. Bivariate and
multivariate logistic regression analyses were employed to identify associated factors for
adherence. P-value less than 0.05 with 95 % confidence interval was used to state the association
between independent predictors and the outcome variable.
Result: A total of 190 HIV+ pregnant & lactating mothers were included in this study. The
level of adherence on option B+ PMTCT drug was 87.9 %. Factors such as those who attend
in Hospital(AOR 0.3,95% CI(0.11-0.82), rural residence (AOR 0.26, 95%CI (0.1-0.73) and
those who faced challenges in the same day diagnosis of HIV and initiating lifelong option
B+ treatment (AOR 0.08, 95%CI (0.02-0.37) were associated factors for adherence
Conclusion & recommendation: mothers who attended for option B+ drugs in health
centers, those who lived in urban area and who had no any challenges in same day diagnosing
& initiating option B+ drugs were significantly associated factors for better adherence to
option B+drugs. Therefore, the ability to effectively handle these factors is crucial in the
success of option B+ programme.
Key words: adherence, Option B+, HIV+ pregnant & lactating mothers, north east Ethiopia
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Keywords
Adherence, Option B+, HIV+ pregnant & lactating mothers, North east Ethiopia