Estimation of serum high sensitivity c-reactive protein and serum lipid profile among hypertensive patients: a cross sectional study at jigjiga, karamara general hospital, Somali regional state of Ethiopia.
| dc.contributor.advisor | Gnana, Natesan (PhD.,Assistance professor) | |
| dc.contributor.author | Ali, Mohamed | |
| dc.date.accessioned | 2018-11-27T08:08:04Z | |
| dc.date.accessioned | 2023-11-29T04:18:20Z | |
| dc.date.available | 2018-11-27T08:08:04Z | |
| dc.date.available | 2023-11-29T04:18:20Z | |
| dc.date.issued | 2018-05 | |
| dc.description.abstract | Introduction: Hypertension and dyslipidemia are the two most important public health anxieties in developing countries and one of the major risk factors for cardiovascular diseases. It has been reported that hypertension is in part an inflammatory disorder, and hypertensive patients have been reported for elevated levels of high-sensitivity C-reactive protein (hsCRP). Therefore, the present study is focused to estimate serum high sensitivity C-reactive protein and serum lipid profiles in hypertensive patients at Karamara General Hospital, Jigjiga Somali Regional State of Ethiopia. Methodology: Comparative case-study was conducted from November 2017 to April 2018. A total of 100 participants, 57 hypertensive patients and 43 normal controls were recruited. Data were collected on socio-demographic factors, anthropometric measurements, blood pressure, high sensitivity C-reactive protein and lipid profiles. Result: The serum levels of high sensitivity C-reactive protein, were significantly higher than their respective cut-off values in hypertensive patients compared to normal controls (p<0.001). Serum triglycerides and total cholesterol were significantly higher in hypertensive patients than in normal controls (p<0.05). However, the mean of low density lipoprotein and high density lipoprotein showed significantly no difference in both hypertensive and normal control participants. High sensitivity C-reactive protein was positively correlated with triglycerides, total cholesterol, and inversely correlated with serum high density lipoproteins. Conclusion: Our study finding may conclude that hypertensive patients in the study area have elevated high sensitivity C-reactive protein, triglycerides and total cholesterol, which may synergize in accelerating other cardiovascular diseases. Our finding may help future strategies for preventing both hypertension and dyslipidimia through proper life style change or Medical management or by the combination of both. High sensitivity C-reactive protein estimation may be recommended in evaluation of all hypertensive patients and preserve the Cardiovascular diseases. | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/123456789/14552 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Addis Ababa Universty | en_US |
| dc.subject | Hypertension, HSCRP, Lipid profiles, and Anthropometric indicators. VIII | en_US |
| dc.title | Estimation of serum high sensitivity c-reactive protein and serum lipid profile among hypertensive patients: a cross sectional study at jigjiga, karamara general hospital, Somali regional state of Ethiopia. | en_US |
| dc.type | Thesis | en_US |