Chemical Transformations of Some Kniphofia Quinones
| dc.contributor.advisor | Dagne Ermias (PhD) | |
| dc.contributor.author | M.Ndegwa John | |
| dc.date.accessioned | 2018-06-20T07:25:52Z | |
| dc.date.accessioned | 2023-11-09T16:17:38Z | |
| dc.date.available | 2018-06-20T07:25:52Z | |
| dc.date.available | 2023-11-09T16:17:38Z | |
| dc.date.issued | 1994-06 | |
| dc.description.abstract | Chemical investigation of the rhizome of Kniphofia fotiosa (Hochst), Asphodelaceae, led to the isolation of a minor product code named KKA-1 (40) . The spectral data suggested that it was a dimer of knipholone (32) and its anthrone (33) . This was further confirmed by reductive cleavage to 4,6- dihydroxy-2- methoxyacetophenone (37), acetylphlorogtucinol (36) , and chrysophanol (5) . It was synthesized from knipholone anthrone (33) through oxidative coupling reactions. The synthesis of 4,6-dihydroxy-2- methoxyacetophenone (37), a consitiuent of AT. fotiosa, is reported. Knipholone (32) was synthesized from knipholone anthrone ( 33) through oxidation. Reductive cleavage of knipholone (32) gave chrysophanol (5), 4,6- dihydroxy-2- methoxyacetophenone (37 ) and acetylphloroglucinol (36) . Bromination of knipholone anthrone (33) resulted in four bromides: 41, 42, 43 and 45 . These bromides were not stable in solution | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/12345678/2056 | |
| dc.language.iso | en | en_US |
| dc.publisher | Addis Ababa Universty | en_US |
| dc.subject | Kniphofia Quinones | en_US |
| dc.title | Chemical Transformations of Some Kniphofia Quinones | en_US |
| dc.type | Thesis | en_US |