Effects of Trypanosomiasis on Hematological and Plasma Biochemical Reference Parameters of Small Ruminants in South West Ethiopia
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Date
2008-06
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Addis Ababa University
Abstract
A study was carried out to investigate the effect of trypanosomiasis on the hematological and plasma biochemical parameters of small ruminants (sheep and goat) at Gera and Seka-Chekorsa districts in the Gojeb valley of Ghibe Omo river system, Jimma Zone, Oromiya region in the southwest of Ethiopia. The mean hematological values of RBC (l1.8±2.8 X106/fll) , PCV (24.2±4.1 %), MCV (21.3±4.7f1), neutrophil (30.6± 12.8%), monocyte (3.2±2%) and basophil (0.8±0.9%) for small ruminants (sheep and goats) raised in high tsetse challenge area \\"ere found to be smaller than the values ofRBC l2.7±3.6 XI06Ifll), pev (26.8±9.8%), MCV (22 .3±8.4f1 ), neutrophil 2.7±10.S%), monocyte (4.6±3.2%) and basophil (0.6±0.8%) in low tsetse chall enge area and the variation was statistically significant (P < O.OS). Smaller values of PCV and MCV in the hematological parameters of small ruminants in the high challenge area could be the cause of microcytic type of anemia. Significant differences (P < O.OS) were also observed bet\\"een heer
and goat species within the high challenge area in the values of MCV .9±4.7f1 for sheep. 20.7±4.6f1 for goats), neutrophil (31.8± 12.8% for sheep, 29.2±12.6% for goats) and monoC)1e (2.9± 1.7% for sheep, 3.S±2.3 %for goats) where the values were found to be higher in sheep than goats . In the biochemical analysis values for AST (84.8±2S.8IU/L), ALT (l3.S ±6.SI U/L). creatinine (1. 1 ±0.2mg/dl), and total protein (4. 9±1.6g/dl) were smaller in small ruminants (sheep and goats) raised in high tsetse challenge area than the values of AST (116.S±44.9IC 'L). ALT (19.1 ±9.IIU/L), reatinine (1.2±0.3mg/dl ), and total protein (7 .6±2.9g/dl) in low challenge area and the difference in values between the areas were significant (P < O.OS). ithin the high challenge area significant di fference in some biochemical arameters (P < O.OS) were also observed between sheep and goat species whereby the values of AST (91.3±2SIC L). AL T (14.3±7.3IU/L), and creatinine .3±7.3mg/dl) were found to be higher in sheep than the values of AST (80.3±46IU/L), ALT (l2. 6±S.4IU/L), and creatinine (1.1±0.2mg/dl) in goats . The study also showed higher values of cholesterol (94.S±32.Smg/dL) in small ruminants (sheep and goats) raised in high tsetse challenge area than the values of cholesterol (61.7±42.1mg/dL) in 10'.\ challenge area whereas the values for triglycerides (93.4±43.7mmollL) were found to be smalkr
than the values for triglycerides (l07.S±37.4mmollL) in the low challenge area and the d ifference in both cases were statistically significant (P < O.OS). Thus it can be concluded from the stue), that trypanosomiasis has a rominent effect on the hematological and plasma biochemica.l VIII
parameters of small ruminants In the high tsetse challenge areas of South Western parts of Ethiopia and attention should be given in utilizing the values of these parameters for assessing the physiological status of animals for diagnostic purpose.Key words: Trypanosomiasis, small ruminant, matological parameters, biochemical parameters, southwest of Ethiopia
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Keywords
Trypanosomiasis