Concordance Between Bethesda Cytology Classification and Acr-Tirads Ultrasound Classification in Evaluation of Thyroid Nodule, at Tikur Anbesa Specialized Hospital, Addis Ababa, Ethiopia: Prospective Study from April, 2023-October, 2023
| dc.contributor.advisor | Dagnachew Tamrat | |
| dc.contributor.author | Birhanu Kassie | |
| dc.date.accessioned | 2025-08-12T20:00:51Z | |
| dc.date.available | 2025-08-12T20:00:51Z | |
| dc.date.issued | 2024-02-02 | |
| dc.description.abstract | Background and objective The Bethesda System for Reporting Thyroid Cytopathology TBSRTC is widely used method currently helping in management of thyroid nodules which are common and mostly benign. The thyroid ultrasound ACR-TIRADS system is also widely used classification system which has helped in screening for nodules requiring subsequent FNAC, but the correlation between the two systems has not been established in our setup. This study aims to determine the level of concordance between TBSRTC cytology category and ACR-TIRADS ultrasound category. Methodology It was a prospective cross-sectional study over 6 months which included 92 patients with thyroid nodule. In all cases the thyroid ultrasound and cytology findings were reported based on ACR-TIRADS and the TBSRTC 2017 system respectively. The level of agreement between ACR-TIRADS and BSRTC systems was expressed as kappa value. Result Study subjects were mostly women (84%), with average age of 47.60 years. The highest frequency in Bethesda system was seen in category II (54/92) and category V (17/92). In contrast, the highest frequency in TIRADS was, in category 4 (45/92) and category 3(21/92). Maximum concordance was found among the category 2-II and 5-V of the classification systems. The overall observed agreement was 65.2% with a linear weighted kappa of 0.343 (95% CI: 0.213 0.472). A higher weighted kappa value was seen in males, nodules ≥4 cm, individuals aged. Conclusion The study revealed a fair concordance between cytologic diagnosis based on the TBSRTC and ultrasound diagnosis based on the ACR-TIRADS, with the highest concordance seen in the two ends of the classification categories (TIRADS5-Bethesda V and TIRADS2-Bethesda II). Careful interpretation of the ultrasound findings and cytologic specimens allow the treating physicians to decide nodules which needs surgery and follow up, so that there will be no unnecessary surgical procedures and complications. There should be an institutional monitoring system for nodules with discordant Bethesda and TIRADS category, especially for those with extreme categories are produced. Key words: Thyroid nodule, Bethesda, Ultrasound, ACR-TIRADS, FNAC, cytologic diagnosis | |
| dc.identifier.uri | https://etd.aau.edu.et/handle/123456789/6491 | |
| dc.language.iso | en_US | |
| dc.publisher | Addis Ababa University | |
| dc.subject | Dagnachew Tamrat | |
| dc.title | Concordance Between Bethesda Cytology Classification and Acr-Tirads Ultrasound Classification in Evaluation of Thyroid Nodule, at Tikur Anbesa Specialized Hospital, Addis Ababa, Ethiopia: Prospective Study from April, 2023-October, 2023 | |
| dc.type | Thesis |