Flame Atomic Absorption Spectrophotometric Determination of some Selected Minerals in Multivitamin Pharmaceutical Dosage forms Marketed in Ethiopia
| dc.contributor.advisor | Ahmed, Adnan( Prof,) | |
| dc.contributor.author | Mengistu, Mequanent | |
| dc.date.accessioned | 2022-03-24T05:36:40Z | |
| dc.date.accessioned | 2023-11-09T16:19:32Z | |
| dc.date.available | 2022-03-24T05:36:40Z | |
| dc.date.available | 2023-11-09T16:19:32Z | |
| dc.date.issued | 2009-12 | |
| dc.description.abstract | Six commercial brands of multivitamins with multimineral marketed in Ethiopia were analyzed for their macro Ca (II), Mg (II) and K (I)) and micro Cr (III and VI)) elemental quantitation , prior to analysis samples were digested in Kjeldahl apparatus with 10 ml analytical grade of o concentrated (67-70) HNO) % w/v and 5 ml of 30% H20 2 w/v healed at a temperature of 150 C in order to remove all the organic matters of multivitamin until a clear solution was obtained. Each sample solution was quantitative ly transferred to 100 ml volumetric flask and adjusted to the mark with deionized water. The calibration curve was linear in the range of 0.001 Ilg/mL to 0.0225 Ilg/mL for magnesium (TI), 0.01 Ilg/mL to 3.00 Ilg/mL of calcium (II), 0.01 Ilg/mL to 1.5 Ilg/ml of potassium (I) and 0.05Ilg/ml to 3.00 Ilg/mL of total clU'omium (III and VI).The correlation coefficients for all standard metallic solutions of Ca (II), Mg (II), K (I) and total Cr . (III and VI) in the linear range of r > 0.998. The precision were evaluated in an inter-day and intera-day determination of magnesium (II) and calcium (II) in Maxamine forte tablets, the RSD and RSE were lower than 2% and the recoveries were carried out and found to be between 98% and 101.0 I % that ascertains good precision of the method. Thus, F AAS was found to be simple to operate, sensitive, precise alld suitable for quantitative determination of metal ions in multivitamin with multimineral preparations and could be useful in a routine work. Key words: FAAS, Wet digestion, Elemental analys is, Multivitamins with multiminerals dosage forms | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/12345678/30785 | |
| dc.language.iso | en | en_US |
| dc.publisher | Addis Ababa University | en_US |
| dc.subject | FAAS | en_US |
| dc.subject | Wetdigestion | en_US |
| dc.subject | Elemental analysis | en_US |
| dc.subject | Multivitamins with multiminerals dosage forms | en_US |
| dc.title | Flame Atomic Absorption Spectrophotometric Determination of some Selected Minerals in Multivitamin Pharmaceutical Dosage forms Marketed in Ethiopia | en_US |
| dc.type | Thesis | en_US |