Investigation of Non-Communicable Diseases Prevalence, Patterns and Outcomes Among Hospitalized patients: A Prospective Observational Study in Three Tertiary Hospitals
| dc.contributor.advisor | Chelkeba,Legese(PhD, Ass.Prof.) | |
| dc.contributor.advisor | Amare,Firehiwot(Ass.Prof.) | |
| dc.contributor.advisor | Guteta,Senbeta(MD, Prof.) | |
| dc.contributor.advisor | Fisseha,Henok(MD) | |
| dc.contributor.author | Belayneh,Alemu | |
| dc.date.accessioned | 2025-08-12T19:35:38Z | |
| dc.date.available | 2025-08-12T19:35:38Z | |
| dc.date.issued | 2024-07 | |
| dc.description.abstract | Background: Non-communicable diseases (NCDs) pose a significant global health challenge, constituting over 71% of overall mortality and morbidity. Cardiovascular diseases, cancer, diabetes mellitus, and chronic respiratory disease are the major classes of NCDs and the leading cause of death globally. Recently, the burden of these NCDs have become more pronounced in low- and middle-income countries, including Ethiopia. Objective: To determine the prevalence, patterns, patient outcome, and pattern of medication use of major NCD among hospitalized population. Methods: A prospective follow-up study was conducted across three tertiary hospitals from October 2022 to January 2023 among hospitalized population. Socio- demographic and clinical data were collected through medical records review and interviews. Descriptive statistics, multinomial logistic regression, survival analysis and negative binomial regression were conducted to summarize, and determine the independent predictor of clinical outcomes, P-value < 0.05 was considered statistically significant. Results: The overall prevalence of NCDs among hospitalized patients was 1302 (58.2%). However, after the exclusion of patients who did not fulfill the inclusion criteria for follow- up, the proportion of NCD among hospitalized patients in our sample became 523 (23.4%), of which 80 (15.3%) faced in-hospital mortality and 90 (17.2%) were discharged with unsatisfactory clinical outcomes. Cardiovascular diseases and cancer were the dominant NCDs among these patients, with a rate of 53% and 30% hospitalization and 13% and 22.7% in- hospital mortality, respectively. Participants diagnosed with cancer showed significantly higher odds of mortality and prolonged hospital stays. Medication non-adherence (AOR: 4.679, 95% CI: 2.48–8.80), the presence of other co-morbid conditions (AOR: 3.81, 95% CI: 2.024–7.19), and the presence of complications (AOR: 10.24, 95% CI: 5.35–19.63) were significant predictor of in-hospital mortality. Conclusion: Our study reveals a substantial prevalence of NCDs among hospitalized patients, primarily with CVDs and cancer. Alarmingly, a significant mortality rate and prolonged hospitalization were observed among patients diagnosed with cancer. | |
| dc.identifier.uri | https://etd.aau.edu.et/handle/123456789/6435 | |
| dc.language.iso | en_US | |
| dc.publisher | Addis Ababa University | |
| dc.subject | Non-communicable disease | |
| dc.subject | clinical outcome | |
| dc.subject | prevalence | |
| dc.subject | treatment | |
| dc.subject | pattern. | |
| dc.title | Investigation of Non-Communicable Diseases Prevalence, Patterns and Outcomes Among Hospitalized patients: A Prospective Observational Study in Three Tertiary Hospitals | |
| dc.type | Thesis |