Prevalence and predictors of hypoglycemia among neonates on admission to NICU in Addis Ababa public Hospitals, Addis Ababa, Ethiopia, 2021.

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Addis Abeba University


Background: Hypoglycemia is one of the most common and preventable metabolic problems seen in the neonatal intensive care unit (NICU). It occurs in 1.3-4.4 per 1000 full- tern newborn and 15-55per 1000 preterm newborns. Studying the prevalence and predictors related with neonatal hypoglycemia, may help in preventing morbidity, serious neurological complications and mortality due to hypoglycemia. Objective: This study aims to determine the prevalence and predictors of hypoglycemia among neonates on admission to NICU in selected public hospitals, Addis Ababa, Ethiopia 2021. Method: Institutional based cross-sectional study was carried out among 317 neonates admitted to neonatal intensive care units in selected public hospitals Addis Ababa .The study participants were selected by systematic random sampling method. Data was collected from February 20/2021 - April 20/2021. Data was collected with a checklist, neonatal chart review, and blood glucose level was checked by pricking the neonate’s heel. A glucometer with a test strip was used to check blood glucose. A blood glucose level < 40mg/dl was taken as a cut-off point to define hypoglycemia for newborn. Then the collected data was coded and entered in to Epi data of version 4.6 and exported to SPSS for windows version 26.0 for cleaning, editing, and analysis. Binary and multiple logistic regressions have been used to observe the association between independent variables and dependent variable. Results: The prevalence of hypoglycemia among public hospitals was 20.8 %. Maternal DM, gestational (AOR=5.16, 95% CI; 1.23-21.64) and pre-gestational DM (AOR =7.79, 95%CI: 1.14-53.03), and preeclampsia (AOR=2.44, 95% CI; 1.10-5.38), feeding initiation time less than one hour [AOR=0.38, 95% CI: 0.15-0.96] shows association to hypoglycemia. Conclusion: The result of this study showed that maternal DM (pre-existing and gestational) and preeclampsia were more likely associated with hypoglycemia, whereas feeding initiation time within one hour was protective effect to hypoglycemia. Therefore early initiation of feeding is important factor to prevent hypoglycemia for all newborns. Recommendation: Health education on preventive measures is very essential for parents and caregivers.



Hypoglycemia, Predictors, Neonatal Intensive Care Unit, Addis Ababa