Chemical Composition of Croton Macrostachys
| dc.contributor.advisor | Abegaz Berhanu (PhD) | |
| dc.contributor.author | Henberu Dirshaye | |
| dc.date.accessioned | 2018-06-18T05:18:10Z | |
| dc.date.accessioned | 2023-11-09T16:17:30Z | |
| dc.date.available | 2018-06-18T05:18:10Z | |
| dc.date.available | 2023-11-09T16:17:30Z | |
| dc.date.issued | 1981-06 | |
| dc.description.abstract | The root~·bark powder of Croton macrostachys Hochstex. A. Rich. (Euphorbeaceae) (ብሳና), used in Ethiopia for curing spreading wounds, was extracted with diethyl ether. The crude extract, on fractionation by column chromatography (Silica gel) yielded a major solid compound A (mp 210'-212o) crystallizable from acetone~methanol (9:1) into beautiful needle aggregates, the structure of -Ihich was identifted, using IR, PMR and MS data, to be that of lupeol, a known antitumor agent. The tumor inhibitory compound Crot-poxide which was previously isolated from the fruits could not be detected in the root~ bark extract. Preliminary investigation also showed the presence of trace solids Band C having the same Rf on TLC. B was water isoluble \.,hi te solid while C was water soluble and sho~led strong blue fluorescence under UV-lamp. The presence of quaternary alkaloid was also confirmed in the root-bark. | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/12345678/1084 | |
| dc.language.iso | en | en_US |
| dc.publisher | Addis Ababa Universty | en_US |
| dc.subject | Croton Macrostachys | en_US |
| dc.title | Chemical Composition of Croton Macrostachys | en_US |
| dc.type | Thesis | en_US |