Bacterial Pathogens and Their Drug Susceptibility Pattern in Children with Aerobic Chronic Suppurative Otitis Media in Addis Ababa
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Date
2000-06
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Addis Ababa University
Abstract
In Ethiopia, as most developing countries there. is little information on chronic
suppurative otitis media. Thus, this study was conducted to establish the causative microorganisms
in chronic suppurative otitis media among children aged 0- I 2 years and to
determine antibiotic treatment based on the information of antimicrobial sensitivity
pattern of the isolates. A structured questionnaire designed for the purposes of this study
was used to collect information from patients as well as parents. A total of 112 (63 males,
49 females) patients consisting 25% of those seen at the ear, nose and throat (ENT)clinic
of the Ethio-Swedish Children's Hospital with problem of chronic suppurative otitis
media were studied. Most of them (83%) were from Addis Ababa. Their age range was
from 3 months to 12 years, 38.4% of them below 2 years of age. Bacterial pathogens
were -isolated fi'om ear discharge of 120/132 (90.1%) swabs with chronic suppurative
otitis media, while the remaining 12/132 (9.9%) were sterile. Of the 159 total isolates,
106 (66.7%) were identified as single pathogens, while 53 (33.3%) were mixed isolates.
The main organisms isolated in the order of frequency were Proteus species, Escherichia
coli, Staphylococcus allrellS, Klebsiella species, Pselldomonas aerllginosa, and
Staphylococclls epiderlllidis. Antibiotic sensitivity test results showed that the majority
of the isolates were sensitive to Gentamicin, Kanamycin and Augmentin. Most of the
isolates were resistant to commonly used antibiotics including, Tetracycline, Ampicillin
and Penicillin. The result of this study showed that these three drugs should be considered
in treating children with chronic suppurative otitis media in our setting. A randomised
controlled clinical trial of these drugs is recommended to establish their in vivo efficacy
and effectiveness studies need to be carried out in a community settings.
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Biology