Jhetstudy of Inborn Errors of Amino Acid Metabolism in Mentally Retarded Subjects in Ethiopia
| dc.contributor.author | Zewdie, Chanyalew | |
| dc.date.accessioned | 2018-06-16T13:56:29Z | |
| dc.date.accessioned | 2023-11-09T16:19:59Z | |
| dc.date.available | 2018-06-16T13:56:29Z | |
| dc.date.available | 2023-11-09T16:19:59Z | |
| dc.date.issued | 1997-02 | |
| dc.description.abstract | Inborn errors of amino acid metabolism are directly related to the absence of an enzyme involved in the metabolism of one or more amino acids, so that those amino acids increase greatly in plasma concentration and urinary excretion rates. Most of these inborn errors of amino acid metabolism are associated with mental retardation. Urine specimens from 345 mentally retarded subjects have been analyzed using qualitative chemical tests and one-dimensional paper chromatography in order to detect any inborn errors of amino acid metabolism which could be associated with mental retardation. The following amino acid abnormalities were discovered: Homocystinuria, 1 case (0.29%); Amino acid malabsorption, 1 case (0.29%); indicanuria, 1 case (0.29); Generalized aminoaciduria, 6 cases (1.78%). | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/12345678/1045 | |
| dc.language.iso | en | en_US |
| dc.publisher | Addis Ababa Universty | en_US |
| dc.subject | Amino Acid Metabolism | en_US |
| dc.title | Jhetstudy of Inborn Errors of Amino Acid Metabolism in Mentally Retarded Subjects in Ethiopia | en_US |
| dc.type | Thesis | en_US |