Assessment of Drug Therapy Problems and Associated Factors Among Ambulatory Patients with Schizophrenia at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia: A Cross-Sectional Study
| dc.contributor.advisor | Shibeshi, Workineh (PhD, Associate Professor of Pharmacology) | |
| dc.contributor.author | Temtem, Gubae | |
| dc.date.accessioned | 2018-12-30T18:29:55Z | |
| dc.date.accessioned | 2023-11-06T08:08:11Z | |
| dc.date.available | 2018-12-30T18:29:55Z | |
| dc.date.available | 2023-11-06T08:08:11Z | |
| dc.date.issued | 2018-12 | |
| dc.description.abstract | Assessment of Drug Therapy Problems and Associated Factors Among Ambulatory Patients with Schizophrenia at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia: A Cross-Sectional Study Gubae Temetem Addis Ababa University, 2018 Among the severe mental disorders schizophrenia is one of the major ones and requires rapid treatment at the early signs of a psychotic incident. In most chronic illness, patients encounter drug therapy problems (DTPs) and if not resolved; the problems may have clinical consequences and causes morbidity, mortality, decreased quality of life, increased health care costs, and can do other harms. Studies regarding DTPs in patients with schizophrenia are insufficient hence; the objective of this study is to assess DTPs and associated factors among ambulatory patients with schizophrenia at Tikur Anbessa Specialized Hospital (TASH). A hospital based cross-sectional study was conducted for a period of 5 months and a total of 118 patients with schizophrenia in psychiatry clinic between July10 and December 8, 2017 were included in the study. The data was then analyzed by using Statistical Package for Social science (SPSS) version 20. The identified DTPs were documented as per the classification of Cipolle. Descriptive statistics, cross-tabulation, binary and multiple logistic regressions were used to analyse the collected patient data and P < 0.05 was considered as significance. The findings of this study showed that the prevalence of DTP was 52.50 %. Adverse drug reaction was the most identified DTP followed by dose low and ineffective drug. The most common drug involved in DTP was risperidone. DTP had a significant association with age, source of medication, duration of schizophrenia treatment and number of medications taken by the patient. The prevalence of medication non adherence was 58.5%. Lack of information about drug side effects, drug product unavailability and/or unaffordability, forgetfulness and patient thought being cured or worse were the major reasons for non adherence. | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/123456789/15358 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Addis Ababa Universty | en_US |
| dc.subject | Schizophrenia, Adherence, Drug therapy problems, Antipsychotic medications. | en_US |
| dc.title | Assessment of Drug Therapy Problems and Associated Factors Among Ambulatory Patients with Schizophrenia at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia: A Cross-Sectional Study | en_US |
| dc.type | Thesis | en_US |