Phytochemical investigation on the Ethanol extract of the aerial parts of Laggera tomentosa
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Date
2009-07
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Addis Ababa Universty
Abstract
Laggera tomentosa in the family of Asteraceae, is a species endemic to Ethiopia.
It has medicinal values and is important in the traditional medicine like the other
species in the genus. In this project work, one sesquiterpene and one flavone,
namely 3-(3’-acetoxy-2’-hydroxy-2’-methylbutyryl)cuauhtemone (LTE-1) and 4’,
5,7-trihydroxy-3’,3,6-trimethoxyflavone (LTE-2) were isolated from the aerial parts
of the plant, respectively. LTE-1 was isolated before from the same plant and
other species of Laggera. LTE-2 was reported before from Jasona montana plant
growing in Egypt and Mentha royleana with the name Jaceidin. However, it was
isolated for the first time from L. tomentosa. The structures were elucidated
based on NMR and UV spectra and by comparison of the data obtained with
those reported for related compounds in the literature
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Keywords
Ethanol extract