A Dissertation Presented to the Faculty of the Graduate School of Arts and Sciences of Braitdeis University, Waltham , Massachusetts
| dc.contributor.advisor | Stevenson, Robert (Professor) | |
| dc.contributor.author | Biftu, Tesfaye | |
| dc.date.accessioned | 2018-07-19T09:30:02Z | |
| dc.date.accessioned | 2023-11-09T16:18:20Z | |
| dc.date.available | 2018-07-19T09:30:02Z | |
| dc.date.available | 2023-11-09T16:18:20Z | |
| dc.date.issued | 1978-08 | |
| dc.description.abstract | 2,3- Diaroylbutanes were selectively converted with high stereospecificity to 2,5~diaryl“3,4-dimethylfurans or 2,3- diarylbutanes. The racemic forms of the dibenzylbutane lignans, dihydroguaiaretic acid dimethyl ether 26a, austrobilignan- 5 26b and austrobilignan-6 26 e * and the diaryltetrahydrofuran lignans, veraguensin 27a and its piperonyl analogue 27 b have been readily synthesized. The synthesis of the dissimilar substituted 2^"diaryltetrahydrofuran austrobilignan- 7 27er was limited by isomer formation and separation difficulty. A short convenient synthesis of the aryltetralin lignan, galbulin 37a and the all-trans tetrahydrofuran lignan, / galbelgiri 31a are also reported. 1,4- Diarylbutanes undergo yield dibenzo [a,c] cyclooctenes. Short synthetic routes to the lignan , (+ )-deoxyschizandrin 43d have been developed from 3,4, 5-trimethoxypropiophenone. | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/12345678/9447 | |
| dc.language.iso | en | en_US |
| dc.publisher | Addis Ababa Universty | en_US |
| dc.subject | Arts and Sciences | en_US |
| dc.title | A Dissertation Presented to the Faculty of the Graduate School of Arts and Sciences of Braitdeis University, Waltham , Massachusetts | en_US |
| dc.type | Thesis | en_US |