Effects of Trypanosomosis on Hematological and Plasma Biochemical Reference Parameters of Small Ruminants in South West Ethiopia
No Thumbnail Available
Date
2008-06
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
A study was carried out to investigate the effect of trypanosomosis on the hematological and plasma biochemical parameters of small ruminants (sheep and goat) at Gera and Seka-Chekorsa districts in the Gojeb valley of Ghibe Omo river system, Jimma Zone, Oromiya region in the southwest of Ethiopia. The mean hematological values of RBC (11.8±2.8 X106/μl), PCV (24.2±4.1%), MCV (21.3±4.7fl), neutrophil (30.6±12.8%), monocyte (3.2±2%) and basophil (0.8±0.9%) for small ruminants (sheep and goats) raised in high tsetse challenge area were found to be smaller than the values of RBC (12.7±3.6 X106/μl ), PCV (26.8±9.8%), MCV (22.3±8.4fl), neutrophil (32.7±10.5%), monocyte (4.6±3.2%) and basophil (0.6±0.8%) in low tsetse challenge area and the variation was statistically significant (P < 0.05). Smaller values of PCV and MCV in the hematological parameters of small ruminants in the high challenge area could be the cause of microcytic type of anemia. Significant differences (P < 0.05) were also observed between sheep and goat species within the high challenge area in the values of MCV (21.9±4.7fl for sheep, 20.7±4.6fl for goats), neutrophil (31.8±12.8% for sheep, 29.2±12.6% for goats) and monocyte (2.9±1.7% for sheep, 3.5±2.3 %for goats) where the values were found to be higher in sheep than goats. In the biochemical analysis values for AST (84.8±25.8IU/L), ALT (13.5±6.5IU/L), creatinine (1.1±0.2mg/dl), and total protein (4.9±1.6g/dl) were smaller in small ruminants (sheep and goats) raised in high tsetse challenge area than the values of AST (116.5±44.9IU/L), ALT (19.1±9.1IU/L), creatinine (1.2±0.3mg/dl), and total protein (7.6±2.9g/dl) in low challenge area and the difference in values between the areas were significant (P < 0.05). Within the high challenge area significant difference in some biochemical parameters (P < 0.05) were also observed between sheep and goat species whereby the values of AST (91.3±25IU/L), ALT (14.3±7.3IU/L), and creatinine (14.3±7.3mg/dl) were found to be higher in sheep than the values of AST (80.3±46IU/L), ALT (12.6±5.4IU/L), and creatinine (1.1±0.2mg/dl) in goats. The study also showed higher values of cholesterol (94.5±32.5mg/dL) in small ruminants (sheep and goats) raised in high tsetse challenge area than the values of cholesterol (61.7±42.1mg/dL) in low challenge area whereas the values for triglycerides (93.4±43.7mmol/L) were found to be smaller than the values for triglycerides (107.5±37.4mmol/L) in the low challenge area and the difference in both cases were statistically significant (P < 0.05). Thus it can be concluded from the study that trypanosomosis has a prominent effect on the hematological and plasma biochemical
IX
parameters of small ruminants in the high tsetse challenge areas of South Western parts of Ethiopia and attention should be given in utilizing the values of these parameters for assessing the physiological status of animals for diagnostic purpose.
Description
Keywords
Trypanosomosis, small ruminant, hematological parameters, biochemical parameters, southwest of Ethiopia