Synthesis Stereochemistry and Dynamic BehaVioI' of Some ThioacrylamideS'
| dc.contributor.advisor | Kleinpeter, E. (PhD) | |
| dc.contributor.author | Tadessm, Tsegaye | |
| dc.date.accessioned | 2018-06-26T08:50:39Z | |
| dc.date.accessioned | 2023-11-09T16:18:05Z | |
| dc.date.available | 2018-06-26T08:50:39Z | |
| dc.date.available | 2023-11-09T16:18:05Z | |
| dc.date.issued | 1984-06 | |
| dc.description.abstract | The reaction of W,N-Dimethylamides with the dimer of p-methoxyphenyl thionophosphine sulfide (Lawesson,' s reagent) gives N,N-Dimethylthioamides. BY treating these disubsti ... tuted thioamides with (i) the Vilsmeir -'Haack Arnold complex (formamide chloride) and (ii) Bis-(dimethylamino)tert- butoxy methane, mode1compounds (Me2N-CHPO(R)~~-NR2) ",ere synthesized. Substitution reactions \'1ere also carried: out using these model compounds (3-aminothioacrylamides) or their imi.nium salts with a primary amine (p-anisidine) to: synthesize the corresponding 3-anisidinothioacrylamides. The reactions were successful and yields \~ere nearly quantitative. The dynamic behaviour and the groUQdstate stereochemistry of these model compounds have been studied. Based on 1H_NMR study and LIS investigation, rotational barriers as well as' the preferred conformation of some of these model compounds have been determined from the proposed three dimensiona:t geometries | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/12345678/3645 | |
| dc.language.iso | en | en_US |
| dc.publisher | Addis Ababa Universty | en_US |
| dc.subject | ThioacrylamideS | en_US |
| dc.title | Synthesis Stereochemistry and Dynamic BehaVioI' of Some ThioacrylamideS' | en_US |
| dc.type | Thesis | en_US |