Phytochemical Investigation on the Aerial Part of Anthemis Tigreensis (Chloroform Extract)

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Addis Ababa Universty


A. tigreensis in the family Asteraceae, in the genus Anthemis is the only species found in Ethiopia. A. tigreensis has medicinal value and is important in traditional medicine like the other species in the genus. Anthemis nobilis (Chamomile) has been known from Roman times as an antispasmodic and sedative in folk treatment of digestive and rheumatic disorders. It is also a popular herb tea. A. cotula shows antimicrobial activity against both Gram-negative and Gram-positive microorganisms. In local medicine, the roots of A.tigreensis are used against wet eczema. In this work, two compounds, At-3(AntheindurolideA) and At-17(dihydro-5-(4-(tetrahydro-3- methylene-2-oxofuran-4-yl)-2-hydroxy-2-methylbut-3-enyl)-3-methylfuran-2(3H)-one were isolated from the aerial part of the plant. At-3 was isolated before from A. tigreensis and other species ofAnthemis. To the best of our knowledge compound At-17 has not been reported before in theNatural Product Dictionary and literature. The structures were elucidated from 1D and 2D-NMR,UV and IR spectra data and by comparison of the data obtained with those reported for thecompounds in the literature.



Anthemis Tigreensis