Sensitivity and Specificity of Fine Needle Aspiration Cytology on Breast Mass as Compared to Histology Evaluation
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Date
2014-10
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Addis Ababa University
Abstract
Introduction: Breast cytology has been used for many years as a diagnostic tool for managing patients with breast lesions. In experienced hands, FNAB was found to be highly sensitive and specific. Objective: To evaluate the accuracy and diagnostic performance of fine needle aspiration FNA cytology in diagnoses of breast masses. Methods: FNA diagnoses and biopsy of breast masses of patients who underwent subsequent histopathologic evaluation during June2013-June2014 at Black lion Hospital pathology laboratory were evaluated. Cytological diagnoses was classified as benign, suspicious for malignancy, malignant, and inadequate or inconclusive and was compared with the histopathologic diagnoses obtained from incisional biopsy or mastectomy specimen to assess the diagnostic performance of FNA. Result and conclusion: The sensitivity and specificity of FNAc was found to be 86.7% and 90.3% respectively. FNA is still proved to be a good diagnostic modality for immediate diagnosis and patient follow up. The positive and negative predictive values are 86.7% and 90.3% respectively.
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Pathology