Meta- Analysis of the Study of Maternal Mortality and Its Associated Factors in Ethiopia

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Addis Ababa University


Background According to the World Health Organization, in 2017 the maternal death rate in Ethiopia was 401 for each 100,000 live births, which albeit essentially decreased from 2010 levels (1030, per 100,000 live births), is still high contrasted with worldwide pace of 211 for every 100,000 live births. Objective The main objective of the study was to examine the key determinants of maternal mortality in Ethiopia. Methods Data were entered into Microsoft Excel and then exported to STATA 16 software for further investigation. Random effect model was used, and the findings of meta-analysis is presented using forest plot, funnel plot, and meta regression table. Forest plots were used to present the combined estimate with 95% confidence interval (CI) of the meta-analysis. Results The factors significantly associated with maternal mortality are having Postpartum hemorrhage OR= 3.50 [ 2.86, 4.14] and antepartum hemorrhage OR=0.45 [ 0.14, 0.76]. The factors that have no significant association with maternal mortality are education, resident, Sepsis and Pregnancy induced hypertension overall effect size (Odds Ratio) with 95% CI of 2.09 [ 0.47, 3.70], 1.19 [ 0.44, 1.94], 0.90 [ -0.33, 2.13] and 0.94 [ -0.18, 2.07] respectively. Conclusions This meta-analysis study finding showed that physiological factors like Antepartum hemorrhage and postpartum hemorrhage have an impact on maternal mortality and highlights risk factors for maternal mortality in Ethiopia. It is also showed the importance of skilled person attended delivery, postnatal care, and maternal education on danger sign of pregnancy and actions to be taken to avoid the three delays that have huge impact on maternal mortality due to the effect of direct causes of occurrence.



Maternal mortality, maternal health, Postpartum hemorrhage, antepartum hemorrhage, education, resident, Sepsis and Pregnancy induced hypertension.