Assessment of Breast Cancer Treatment Outcome at Tikur Anbessa Specialized Hospital Adult Oncology Unit, Addis Ababa, Ethiopia
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Date
2016-01
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Addis Ababa University
Abstract
Breast cancer is a leading cause of death worldwide, and ranks as the fifth cause of death from all cancers, and the most common cause of cancer death in women in both developing and developed countries. However, information regarding treatment outcome of breast cancer is scarce in Ethiopia. The aim of this study was therefore to assess treatment outcome among breast cancer patients at Tikur Anbessa Specialized Hospital adult oncology unit. To this effect a hospital, based retrospective cross-sectional study was conducted. Data were collected by reviewing the medical records and by phone interview. A total of 303 patients were included in the study, more than one fourth (31.02%) of the patients were in the age range of 30-39 years, with a mean age of 42.10 years. More than half (54.10%) of the patients were diagnosed to have breast cancer with clinical tumor, nodal status and metastasis stage III. The frequently used combination chemotherapy was FAC (5-fluorouracil, Doxorubicin, and Cyclophosphamide) in (66.9%) patients. At the end of three years treatment follow up, (46.53%) of patients were dead, while 34.32% were alive. The result of logistic regression analysis showed that age (AOR= 0.32, 95% CI: 0.12, 0.95, P=0.040), chemotherapy cycle (AOR= 7.36, 95% CI: 2.28, 23.79, P=0.001), stage of the disease (AOR= 0.11, 95% CI: 0.05, 0.29, P=0.000), endocrine therapy (AOR= 0.09, 95% CI: 0.04, 0.22, P=0.000) were significantly associated with the outcome of death. Treatment outcome of breast cancer is poor
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and requires health education and sensitization on preventive approach through screening to prevent the late stage presentation at health facilities.
Key words: Breast cancer, treatment outcomes, treatment options, stage of cancer
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Breast cancer;Treatment outcomes; Treatment options; Stage of cancer